[HTML][HTML] Natural anti-inflammatory compounds as drug candidates for inflammatory bowel disease

L Duan, S Cheng, L Li, Y Liu, D Wang… - Frontiers in …, 2021 - frontiersin.org
Inflammatory bowel disease (IBD) represents chronic recurrent intestinal inflammation
resulting from various factors. Crohn's disease (CD) and ulcerative colitis (UC) have been …

[HTML][HTML] Cellular and molecular therapeutic targets in inflammatory bowel disease—focusing on intestinal barrier function

I Schoultz, ÅV Keita - Cells, 2019 - mdpi.com
The human gut relies on several cellular and molecular mechanisms to allow for an intact
and dynamical intestinal barrier. Normally, only small amounts of luminal content pass the …

A nanoparticulate dual scavenger for targeted therapy of inflammatory bowel disease

C Shi, J Dawulieti, F Shi, C Yang, Q Qin, T Shi… - Science …, 2022 - science.org
A therapeutic strategy that targets multiple proinflammatory factors in inflammatory bowel
disease (IBD) with minimal systemic side effects would be attractive. Here, we develop a …

[HTML][HTML] Turmeric-derived nanovesicles as novel nanobiologics for targeted therapy of ulcerative colitis

C Gao, Y Zhou, Z Chen, H Li, Y Xiao, W Hao, Y Zhu… - Theranostics, 2022 - ncbi.nlm.nih.gov
Abstract Rationale: Ulcerative colitis (UC), a typical kind of inflammatory bowel disease
(IBD), is an idiopathic chronic intestinal inflammation. Conventional therapeutic strategies …

[HTML][HTML] Colon stroma mediates an inflammation-driven fibroblastic response controlling matrix remodeling and healing

GJ Jasso, A Jaiswal, M Varma, T Laszewski… - PLoS …, 2022 - journals.plos.org
Chronic inflammation is often associated with the development of tissue fibrosis, but how
mesenchymal cell responses dictate pathological fibrosis versus resolution and healing …

STAT3-mediated ferroptosis is involved in ulcerative colitis

F Huang, S Zhang, X Li, Y Huang, S He… - Free Radical Biology and …, 2022 - Elsevier
Ferroptosis is a form of iron-dependent lipid peroxidation cell death that plays an important
role in inflammation. However, the mechanism of ferroptosis in ulcerative colitis (UC) …

[HTML][HTML] The role of tissue-resident macrophages in the development and treatment of inflammatory bowel disease

S Ma, J Zhang, H Liu, S Li, Q Wang - Frontiers in cell and …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD), comprising Crohn's disease and ulcerative colitis, is a
refractory disease with many immune abnormalities and pathologies in the gastrointestinal …

[HTML][HTML] The efficacy of probiotics, prebiotic inulin-type fructans, and synbiotics in human ulcerative colitis: a systematic review and meta-analysis

E Astó, I Méndez, S Audivert, A Farran-Codina… - Nutrients, 2019 - mdpi.com
Studies of probiotics, fructan-type prebiotics, and synbiotics in patients with ulcerative colitis
(UC) show significant heterogeneity in methodology and results. Here, we study the efficacy …

Eurotium cristatum, a Probiotic Fungus from Fuzhuan Brick Tea, and Its Polysaccharides Ameliorated DSS-Induced Ulcerative Colitis in Mice by Modulating the Gut …

X Lu, Y Jing, N Zhang, Y Cao - Journal of Agricultural and Food …, 2022 - ACS Publications
Eurotium cristatum is a potential probiotic fungus that is used to enhance Fuzhuan tea
quality through fermentation and could reduce obesity by modulating gut dysbiosis. This …

[HTML][HTML] Natural product-based nanomedicine in treatment of inflammatory bowel disease

T Khare, SS Palakurthi, BM Shah, S Palakurthi… - International journal of …, 2020 - mdpi.com
Many synthetic drugs and monoclonal antibodies are currently in use to treat Inflammatory
Bowel Disease (IBD). However, they all are implicated in causing severe side effects and …