The endocannabinoid system: a potential target for the treatment of various diseases

H Lowe, N Toyang, B Steele, J Bryant… - International journal of …, 2021 - mdpi.com
The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …

Cannabinoids: therapeutic use in clinical practice

C Pagano, G Navarra, L Coppola, G Avilia… - International journal of …, 2022 - mdpi.com
Medical case reports suggest that cannabinoids extracted from Cannabis sativa have
therapeutic effects; however, the therapeutic employment is limited due to the psychotropic …

Industrial Hemp (Cannabis sativa subsp. sativa) as an Emerging Source for Value-Added Functional Food Ingredients and Nutraceuticals

HPV Rupasinghe, A Davis, SK Kumar, B Murray… - Molecules, 2020 - mdpi.com
Industrial hemp (Cannabis sativa L., Cannabaceae) is an ancient cultivated plant originating
from Central Asia and historically has been a multi-use crop valued for its fiber, food, and …

Cannabis-based products for chronic pain: a systematic review

MS McDonagh, BJ Morasco, J Wagner… - Annals of internal …, 2022 - acpjournals.org
Background: Contemporary data are needed about the utility of cannabinoids in chronic
pain. Purpose: To evaluate the benefits and harms of cannabinoids for chronic pain. Data …

Neuropathic pain: mechanism-based therapeutics

K Bannister, J Sachau, R Baron… - Annual review of …, 2020 - annualreviews.org
Neuropathic pain (NeP) can result from sources as varied as nerve compression,
channelopathies, autoimmune disease, and incision. By identifying the neurobiological …

Cannabis sativa L. as a Natural Drug Meeting the Criteria of a Multitarget Approach to Treatment

A Stasiłowicz, A Tomala, I Podolak… - International journal of …, 2021 - mdpi.com
Cannabis sativa L. turned out to be a valuable source of chemical compounds of various
structures, showing pharmacological activity. The most important groups of compounds …

Cannabis: a toxin-producing plant with potential therapeutic uses

Z Breijyeh, B Jubeh, SA Bufo, R Karaman, L Scrano - Toxins, 2021 - mdpi.com
For thousands of years, Cannabis sativa has been utilized as a medicine and for
recreational and spiritual purposes. Phytocannabinoids are a family of compounds that are …

A review of scientific evidence for THC: CBD oromucosal spray (nabiximols) in the management of chronic pain

MA Überall - Journal of pain research, 2020 - Taylor & Francis
The 20% prevalence of chronic pain in the general population is a major health concern
given the often profound associated impairment of daily activities, employment status, and …

The role of cannabidiol (CBD) in chronic pain management: an assessment of current evidence

S Boyaji, J Merkow, RNM Elman, AD Kaye… - Current pain and …, 2020 - Springer
Abstract Purpose of Review Given the growing challenges in chronic pain management
coupled with the ongoing consequences of the opioid epidemic, pain management …

Cannabis, cannabinoids and cannabis-based medicines in cancer care

DI Abrams - Integrative cancer therapies, 2022 - journals.sagepub.com
As medical cannabis becomes legal in more states, cancer patients are increasingly
interested in the potential utility of the ancient botanical in their treatment regimen. Although …