The miR-200 family of microRNAs: fine tuners of epithelial-mesenchymal transition and circulating cancer biomarkers

I Cavallari, F Ciccarese, E Sharova, L Urso… - Cancers, 2021 - mdpi.com
Simple Summary MicroRNAs (miRNAs) are small RNA molecules that regulate gene
expression by blocking translation or inducing degradation of specific gene transcripts. The …

SingmiR: a single-cell miRNA alignment and analysis tool

A Engel, S Rishik, P Hirsch, V Keller… - Nucleic Acids …, 2024 - academic.oup.com
Single-cell RNA sequencing (RNA-seq) has revolutionized our understanding of cell
biology, developmental and pathophysiological molecular processes, paving the way …

[HTML][HTML] Biomarkers in renal cell carcinoma and their targeted therapies: a review

S Gupta, SS Kanwar - Exploration of Targeted Anti-tumor Therapy, 2023 - ncbi.nlm.nih.gov
Renal cell carcinoma (RCC) is one of the most life-threatening urinary malignancies
displaying poor response to radiotherapy and chemotherapy. Although in the recent past …

[HTML][HTML] Comprehensive analysis of transcriptome-wide expression patterns and a circRNA/lncRNA-miRNA-mRNA network in the pathogenesis of cerebral ischemia …

YH Yang, HT Tian, XF Jin, D Zhou, YM Ji… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Background: Although ischemic stroke exhibits a high prevalence in the elderly population,
the involved genes and pathways are poorly understood. In this study, we proposed to …

[HTML][HTML] Evaluation of miR-141-3p over-expression in ovarian cancer

L Shi, HJ Sun, JJ Zeng, ZQ Liang, YH Lin… - Electronic Journal of …, 2022 - Elsevier
Background The expression of miR-141-3p in many malignant tumors has been verified.
Nevertheless, the relationship between ovarian cancer and miR-141-3p remains …

miR‐200a‐3p inhibits the PDGF‐BB‐induced proliferation of VSMCs by affecting their phenotype‐associated proteins

RY Zeng, HY Jin, YB Peng, WJ Wang… - … of Biochemical and …, 2024 - Wiley Online Library
Accumulating evidence shows that the abnormal proliferation and migration of vascular
smooth muscle cells (VSMCs) can significantly affect the long‐term prognosis of coronary …

[HTML][HTML] miR-429 通过调控靶基因LRP1 抑制乳腺癌细胞增殖

纪涵青, 吴琍 - Advances in Clinical Medicine, 2022 - hanspub.org
目的: 分析miR-429 对乳腺癌细胞增殖的抑制作用, 通过分析miR-429 对其靶基因的调控方式
研究miR-429 抑制乳腺癌细胞增殖的分子机制. 方法: RT-qPCR 技术检测乳腺癌组织及体外 …

A heavy-tailed model for analyzing miRNA-seq raw read counts

A Krutto, T Haugdahl Nøst, M Thoresen - Statistical Applications in …, 2024 - degruyter.com
This article addresses the limitations of existing statistical models in analyzing and
interpreting highly skewed miRNA-seq raw read count data that can range from zero to …