A major question that remains unanswered concerning endothelial cell (EC) morphogenesis
is how lumens are formed in three-dimensional extracellular matrices (ECMs). Studies from …

Here, we define an endothelial cell (EC) lumen signaling complex involving Cdc42, Par6b,
Par3, junction adhesion molecule (Jam)–B and Jam-C, membrane type 1–matrix …

Recent data have revealed new mechanisms that underlie endothelial cell (EC) lumen
formation during vascular morphogenic events in development, wound repair, and other …

In order to design scaffolds for tissue engineering with proper architectures, organization
and properties, a variety of materials and technologies are being developed. In addition to …

Expression of several actin-binding proteins including profilin-1 is up-regulated during
capillary morphogenesis of endothelial cells, the biological significance of which remains …

Maintenance of endothelial cell tube integrity is dependent on an intact cytoskeleton. We
present data indicating that rapid collapse of endothelial tubular networks in vitro occurs in a …

Here we describe a microfluidic device that accurately reproduces the dynamics of vascular
anastomosis, the process by which vascular sprouts connect to achieve perfusion during …

Angiogenesis is necessary during embryonic development and wound healing but can be
detrimental in pathologies, including cancer. Because initiation of angiogenesis involves …

Since the survival of ingrowing cells in biomaterials for regenerative processes largely
depends on the supply of nutrients and oxygen, angiogenesis plays an important role in the …

In this review, we discuss the identification of distinct matrix metalloproteinases (MMPs) and
their inhibitors that differentially control the processes of capillary tube formation …