Background We sought to determine the prevalence of germline pathogenic variants (gPVs)
in unselected patients with endometrial cancer (EC), define biallelic gPVs within tumors, and …

Background Patients with cancer seen in rural and underserved areas disproportionately
face barriers to access genetic services. Genetic testing is critical to inform treatment …

Purpose: To explore the role of NBN as a pan-cancer susceptibility gene. Experimental
Design: Matched germline and somatic DNA samples from 34,046 patients were sequenced …

Simple Summary The occurrence of second primary cancers (SPCs) in patients with pleural
mesothelioma (PM) included in the Lombardy Mesothelioma Registry (Italy) was …

Improved cancer screening and treatment programs have led to an increased survivorship of
patients with cancer, but consequently also to the rise in number of individuals with multiple …

The occurrence of multiple primary cancers (MPC) is thought to reflect increased cancer
susceptibility in patients due to a combination of genetic and environmental factors. Here we …

A 59-year-old man was admitted to our hospital in August 2020 because of fever with night
sweats and weight loss. The patient was eventually diagnosed with synchronous triple …

Background With improving survival after pancreatic cancer (PC) resection, questions
emerge concerning risk and patterns of metachronous tumors. We aimed to determine the …

乳腺癌和肺癌是我国最常见的两种恶性肿瘤。 随着乳腺癌诊断和治疗技术的不断提高，
乳腺癌患者的生存时间得以延长， 乳腺癌患者再发第二原发性肺癌（ second primary lung …

Purpose The aim of this study was to investigate the demographic and molecular
characteristics, overall survival (OS), cancer-specific survival (CSS), and prognostic factors …