Dysfunction of the corticostriatal pathway in autism spectrum disorders

W Li, L Pozzo‐Miller - Journal of neuroscience research, 2020 - Wiley Online Library
The corticostriatal pathway that carries sensory, motor, and limbic information to the striatum
plays a critical role in motor control, action selection, and reward. Dysfunction of this …

The conundrums of understanding genetic risks for autism spectrum disorders

MW State, P Levitt - Nature neuroscience, 2011 - nature.com
Recent advances in the genetics of autism spectrum disorders (ASDs) are offering new
valuable insights into molecular and cellular mechanisms of pathology. At the same time, the …

Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia

A Gialluisi, TFM Andlauer, N Mirza-Schreiber… - Translational …, 2019 - nature.com
Developmental dyslexia (DD) is one of the most prevalent learning disorders, with high
impact on school and psychosocial development and high comorbidity with conditions like …

[HTML][HTML] A psycholinguistic framework for diagnosis and treatment planning of developmental speech disorders

H Terband, B Maassen, E Maas - Folia Phoniatrica et Logopaedica, 2019 - karger.com
Background: Differential diagnosis and treatment planning of developmental speech
disorders (DSD) remains a major challenge in paediatric speech-language pathology …

[HTML][HTML] Co-localisation of abnormal brain structure and function in specific language impairment

NA Badcock, DVM Bishop, MJ Hardiman, JG Barry… - Brain and language, 2012 - Elsevier
We assessed the relationship between brain structure and function in 10 individuals with
specific language impairment (SLI), compared to six unaffected siblings, and 16 unrelated …

Foxp2 mediates sex differences in ultrasonic vocalization by rat pups and directs order of maternal retrieval

JM Bowers, M Perez-Pouchoulen… - Journal of …, 2013 - Soc Neuroscience
The FOXP2 gene is central to acquisition of speech and language in humans and vocal
production in birds and mammals. Rodents communicate via ultrasonic vocalizations (USVs) …

The genetics of autism: key issues, recent findings, and clinical implications

P El-Fishawy - Psychiatric clinics, 2010 - psych.theclinics.com
Autism is an often debilitating disorder of development with a worldwide prevalence of
approximately 0.1%. 1 The clinical hallmarks include fundamental deficits in social …

CNTNAP2 variants affect early language development in the general population

AJO Whitehouse, DVM Bishop, QW Ang… - Genes, Brain and …, 2011 - Wiley Online Library
Early language development is known to be under genetic influence, but the genes affecting
normal variation in the general population remain largely elusive. Recent studies of disorder …

Restrictions on biological adaptation in language evolution

N Chater, F Reali… - Proceedings of the …, 2009 - National Acad Sciences
Language acquisition and processing are governed by genetic constraints. A crucial
unresolved question is how far these genetic constraints have coevolved with language …

Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility

C O'Dushlaine, E Kenny, E Heron, G Donohoe… - Molecular …, 2011 - nature.com
Susceptibility to schizophrenia and bipolar disorder may involve a substantial, shared
contribution from thousands of common genetic variants, each of small effect. Identifying …