Dysfunction of the corticostriatal pathway in autism spectrum disorders
W Li, L Pozzo‐Miller - Journal of neuroscience research, 2020 - Wiley Online Library
The corticostriatal pathway that carries sensory, motor, and limbic information to the striatum
plays a critical role in motor control, action selection, and reward. Dysfunction of this …
plays a critical role in motor control, action selection, and reward. Dysfunction of this …
The conundrums of understanding genetic risks for autism spectrum disorders
Recent advances in the genetics of autism spectrum disorders (ASDs) are offering new
valuable insights into molecular and cellular mechanisms of pathology. At the same time, the …
valuable insights into molecular and cellular mechanisms of pathology. At the same time, the …
Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia
A Gialluisi, TFM Andlauer, N Mirza-Schreiber… - Translational …, 2019 - nature.com
Developmental dyslexia (DD) is one of the most prevalent learning disorders, with high
impact on school and psychosocial development and high comorbidity with conditions like …
impact on school and psychosocial development and high comorbidity with conditions like …
[HTML][HTML] A psycholinguistic framework for diagnosis and treatment planning of developmental speech disorders
Background: Differential diagnosis and treatment planning of developmental speech
disorders (DSD) remains a major challenge in paediatric speech-language pathology …
disorders (DSD) remains a major challenge in paediatric speech-language pathology …
[HTML][HTML] Co-localisation of abnormal brain structure and function in specific language impairment
NA Badcock, DVM Bishop, MJ Hardiman, JG Barry… - Brain and language, 2012 - Elsevier
We assessed the relationship between brain structure and function in 10 individuals with
specific language impairment (SLI), compared to six unaffected siblings, and 16 unrelated …
specific language impairment (SLI), compared to six unaffected siblings, and 16 unrelated …
Foxp2 mediates sex differences in ultrasonic vocalization by rat pups and directs order of maternal retrieval
JM Bowers, M Perez-Pouchoulen… - Journal of …, 2013 - Soc Neuroscience
The FOXP2 gene is central to acquisition of speech and language in humans and vocal
production in birds and mammals. Rodents communicate via ultrasonic vocalizations (USVs) …
production in birds and mammals. Rodents communicate via ultrasonic vocalizations (USVs) …
The genetics of autism: key issues, recent findings, and clinical implications
P El-Fishawy - Psychiatric clinics, 2010 - psych.theclinics.com
Autism is an often debilitating disorder of development with a worldwide prevalence of
approximately 0.1%. 1 The clinical hallmarks include fundamental deficits in social …
approximately 0.1%. 1 The clinical hallmarks include fundamental deficits in social …
CNTNAP2 variants affect early language development in the general population
AJO Whitehouse, DVM Bishop, QW Ang… - Genes, Brain and …, 2011 - Wiley Online Library
Early language development is known to be under genetic influence, but the genes affecting
normal variation in the general population remain largely elusive. Recent studies of disorder …
normal variation in the general population remain largely elusive. Recent studies of disorder …
Restrictions on biological adaptation in language evolution
N Chater, F Reali… - Proceedings of the …, 2009 - National Acad Sciences
Language acquisition and processing are governed by genetic constraints. A crucial
unresolved question is how far these genetic constraints have coevolved with language …
unresolved question is how far these genetic constraints have coevolved with language …
Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility
Susceptibility to schizophrenia and bipolar disorder may involve a substantial, shared
contribution from thousands of common genetic variants, each of small effect. Identifying …
contribution from thousands of common genetic variants, each of small effect. Identifying …