Deep phenotyping of Parkinson's disease

E Dorsey, L Omberg, E Waddell… - Journal of …, 2020 - content.iospress.com
Phenotype is the set of observable traits of an organism or condition. While advances in
genetics, imaging, and molecular biology have improved our understanding of the …

The motor prodromes of parkinson's disease: from bedside observation to large-scale application

C Simonet, A Schrag, AJ Lees, AJ Noyce - Journal of Neurology, 2021 - Springer
There is sufficient evidence that the pathological process that causes Parkinson's disease
begins years before the clinical diagnosis is made. Over the last 15 years, there has been …

Mediterranean diet is associated with a lower probability of prodromal Parkinson's disease and risk for Parkinson's disease/dementia with Lewy bodies: a longitudinal …

MI Maraki, M Yannakoulia… - European Journal of …, 2023 - Wiley Online Library
Background and purpose Lifestyle factors have been implicated in the long‐lasting
neurodegenerative process in prodromal Parkinson's disease (pPD). The aim was to …

Ketogenic therapy for Parkinson's disease: A systematic review and synthesis without meta-analysis of animal and human trials

MG Grammatikopoulou, G Tousinas, C Balodimou… - Maturitas, 2022 - Elsevier
Objective The aim of the present systematic review was to assess the efficacy of ketogenic
therapy in Parkinson's disease (PD), using all available data from randomized controlled …

Association between motor signs and cognitive performance in cognitively unimpaired older adults: a cross-sectional study using the NACC Database

V Siokas, I Liampas, CG Lyketsos, E Dardiotis - Brain Sciences, 2022 - mdpi.com
Aiming to examine whether specific motor signs are associated with worse performance in
specific cognitive domains among cognitively unimpaired (CU) individuals, we performed a …

Dietary Inflammatory Index score and prodromal Parkinson's disease incidence: The HELIAD study

V Balomenos, L Bounou, S Charisis… - The Journal of …, 2022 - Elsevier
The aim of the present study was to investigate the association of the inflammatory potential
of diet with prodromal Parkinson's disease (pPD) probability and incidence among …

Plasma glutathione and prodromal Parkinson's disease probability

S Charisis, E Ntanasi, M Stamelou… - Movement …, 2022 - Wiley Online Library
Background A decrease in glutathione (GSH) levels is considered one of the earliest
biochemical changes in Parkinson's disease (PD). Objective The authors explored the …

[HTML][HTML] Association of the polygenic risk score with the probability of prodromal Parkinson's disease in older adults

MI Maraki, A Hatzimanolis, N Mourtzi… - Frontiers in Molecular …, 2021 - frontiersin.org
Several studies have investigated the association of the Parkinson's disease (PD) polygenic
risk score (PRS) with several aspects of well-established PD. We sought to evaluate the …

A prospective validation of the updated movement disorders society research criteria for prodromal Parkinson's disease

N Giagkou, MI Maraki, M Yannakoulia… - Movement …, 2020 - Wiley Online Library
Objective The objective of this study was to validate the recently updated research criteria for
prodromal Parkinson's disease (pPD) proposed by the International Parkinson's Disease …

Subjects at risk of Parkinson's disease in health checkup examinees: cross-sectional analysis of baseline data of the NaT-PROBE study

M Hattori, T Tsuboi, K Yokoi, Y Tanaka, M Sato… - Journal of …, 2020 - Springer
Introduction The present study aimed to survey the prevalence of prodromal symptoms of
Parkinson's disease (PD) in Japanese health checkup examinees, for identifying at-risk …