Long noncoding RNAs: regulation, function and cancer

A Rafiee, F Riazi-Rad, M Havaskary… - … and Genetic Engineering …, 2018 - Taylor & Francis
Long noncoding RNAs (lncRNAs) are non-protein-coding RNA transcripts that exert a key
role in many cellular processes and have potential toward addressing disease etiology …

Multiple functions of long non‐coding RNAs in oxidative stress, DNA damage response and cancer progression

SS Tehrani, A Karimian, H Parsian… - Journal of cellular …, 2018 - Wiley Online Library
In addition to aberrant alternation of transcriptome, it is now suggested that dysregulation of
the non‐coding transcripts, particularly long non‐coding RNAs (lncRNAs), which comprise …

Long noncoding RNA PCAT1, a novel serum-based biomarker, enhances cell growth by sponging miR-326 in oesophageal squamous cell carcinoma

L Huang, Y Wang, J Chen, Y Wang, Y Zhao… - Cell death & …, 2019 - nature.com
Long noncoding RNAs (lncRNAs) play important roles in the development and progression
of human cancers. The lncRNA prostate cancer-associated transcript 1 (PCAT1) has been …

Upregulation of the long noncoding RNA PCAT-1 correlates with advanced clinical stage and poor prognosis in esophageal squamous carcinoma

W Shi, Q Wu, S Li, T Yang, Z Liu, Y Tong, L Tuo… - Tumor Biology, 2015 - Springer
Recent studies reveal that long noncoding RNAs (lncRNAs) play critical regulatory roles in
cancer biology. Prostate cancer-associated ncRNA transcript 1 (PCAT-1) is one of the …

Knockdown of long non-coding RNA prostate cancer-associated ncRNA transcript 1 inhibits multidrug resistance and c-Myc-dependent aggressiveness in colorectal …

L Qiao, X Liu, Y Tang, Z Zhao, J Zhang… - Molecular and cellular …, 2018 - Springer
The long non-coding RNA (lncRNA) prostate cancer-associated ncRNA transcript 1 (PCAT-
1) has been shown to promote prostate cancer cell proliferation through c-Myc and is …

Long non-coding RNA PCAT-1 over-expression promotes proliferation and metastasis in gastric cancer cells through regulating CDKN1A

M Bi, H Yu, B Huang, C Tang - Gene, 2017 - Elsevier
Prostate cancer-associated transcript1 (PCAT-1) is a novel lncRNA that involved in cell
apoptosis and proliferation of prostate cancer. However, the role of PCAT-1 on gastric …

Lineage Plasticity and Stemness Phenotypes in Prostate Cancer: Harnessing the Power of Integrated “Omics” Approaches to Explore Measurable Metrics

S Logotheti, E Papadaki, V Zolota, C Logothetis… - Cancers, 2023 - mdpi.com
Simple Summary Prostate cancer remains the most frequent cause of cancer morbidity, the
second most frequent cause of cancer mortality in men in the developed world and is an …

[HTML][HTML] Expression analysis of long non-coding PCAT-1in breast cancer

S Sarrafzadeh, L Geranpayeh… - International journal of …, 2017 - ncbi.nlm.nih.gov
Background: The prostate cancer-associated non-coding RNA transcript 1 (PCAT-1) is a
newly identified long non-coding RNA whose participation in tumorigenesis of a variety of …

PCAT1: An oncogenic lncRNA in diverse cancers and a putative therapeutic target

S Ghafouri-Fard, S Dashti, M Taheri - Experimental and Molecular …, 2020 - Elsevier
The critical roles of long non-coding RNAs (lncRNAs) in the regulation of diverse biological
functions has potentiated them as cancer biomarkers. Among these transcripts is the …

Variations in genomic regions encoding long non-coding RNA genes associated with increased prostate cancer risk

E Bozgeyik - Mutation Research/Reviews in Mutation Research, 2023 - Elsevier
From a single restriction fragment length polymorphism analysis to next generation
sequencing analysis that screens the entire human genome, testing for genomic variations …