Oxymatrine: A current overview of its health benefits

DQ Huan, NQ Hop, NT Son - Fitoterapia, 2023 - Elsevier
Oxymatrine (OMT), was identified as a quinolizidine alkaloid, which was one of the major
matrine-type alkaloids extracted from Sophora medicinal plants. Growing studies revealed …

Quinolizidine alkaloids derivatives from Sophora alopecuroides Linn: Bioactivities, structure-activity relationships and preliminary molecular mechanisms

Y Li, G Wang, J Liu, L Ouyang - European Journal of Medicinal Chemistry, 2020 - Elsevier
Quinolizidine alkaloids, as essential active ingredients extracted from Sophora
alopecuroides Linn, have been well concerned in the past several decades owing to the …

Structural characterization, antioxidant and hepatoprotective activities of polysaccharides from Sophorae tonkinensis Radix

L Cai, S Zou, D Liang, L Luan - Carbohydrate Polymers, 2018 - Elsevier
In current study we present two polysaccharides, STRP1 and STRP2, purified from
Sophorae tonkinensis Radix via column chromatography. Structural analyses indicated that …

(−)-Cytisine and derivatives: synthesis, reactivity, and applications

J Rouden, MC Lasne, J Blanchet, J Baudoux - Chemical reviews, 2014 - ACS Publications
(−)-Cytisine (−)-1,[(1R, 5S)-1, 2, 3, 4, 5, 6-hexahydro-1, 5-methano-8H-pyrido [1, 2a][1, 5]
diazocin-8-one (Figure 1), is an alkaloid extracted from various plants belonging to the …

In silico analysis of selected alkaloids against main protease (Mpro) of SARS-CoV-2

S Garg, A Roy - Chemico-Biological Interactions, 2020 - Elsevier
In the present situation, COVID-19 has become the global health concern due to its high
contagious nature. It initially appeared in December 2019 in Wuhan, China and now …

Antiviral Matrine-Type Alkaloids from the Rhizomes of Sophora tonkinensis

QM Pan, YH Li, J Hua, FP Huang… - Journal of natural …, 2015 - ACS Publications
Three new matrine-type alkaloids,(+)-5α-hydroxyoxysophocarpine (1),(−)-12β-
hydroxyoxysophocarpine (2), and (+)-5α-hydroxylemannine (3), along with 14 known …

Quinolizidine-type alkaloids: chemodiversity, occurrence, and bioactivity

W Cely-Veloza, MJ Kato, E Coy-Barrera - ACS omega, 2023 - ACS Publications
Quinolizidine alkaloids (QAs) are nitrogen-containing compounds produced naturally as
specialized metabolites distributed in plants and animals (eg, frogs, sponges). The present …

Dimeric Matrine-Type Alkaloids from the Roots of Sophora flavescens and Their Anti-Hepatitis B Virus Activities

YB Zhang, LQ Zhan, GQ Li, F Wang… - The Journal of …, 2016 - ACS Publications
Six unusual matrine-type alkaloid dimers, flavesines A–F (1–6, respectively), together with
three proposed biosynthetic intermediates (7–9) were isolated from the roots of Sophora …

Sophalines E–I, Five Quinolizidine-Based Alkaloids with Antiviral Activities against the Hepatitis B Virus from the Seeds of Sophora alopecuroides

YB Zhang, L Yang, D Luo, NH Chen, ZN Wu… - Organic …, 2018 - ACS Publications
Five novel quinolizidine-based alkaloids (1–5) were obtained from the seeds of Sophora
alopecuroides L. Compounds 1 and 2 are the first examples of sparteine-indolizine and …

Quinolizidine alkaloids from Sophora tonkinensis and their anti-inflammatory activities

LJ He, JS Liu, D Luo, YR Zheng, YB Zhang, GC Wang… - Fitoterapia, 2019 - Elsevier
Two new quinolizidine-based alkaloids (2 and 12), along with ten known ones (1, 3–11)
were isolated from the roots of S. tonkinensis. Their structures were determined by …