Pioneering research studies, beginning with those using Drosophila, have identified several
molecular and cellular mechanisms for active forgetting. The currently known mechanisms …

Hippocampal network operations supporting spatial navigation and declarative memory are
traditionally interpreted in a framework where each hippocampal area, such as the dentate …

The medial temporal lobe, including the hippocampus, has been implicated in social
memory. However, it remains unknown which parts of these brain regions and their circuits …

Memory retrieval involves the interaction between external sensory or internally generated
cues and stored memory traces (or engrams) in a process termed 'ecphory'. While ecphory …

Recent results suggest that social memory requires the dorsal hippocampal CA2 region as
well as a subset of ventral CA1 neurons. However, it is unclear whether dorsal CA2 and …

Collections of cells called engrams are thought to represent memories. Although there has
been progress in identifying and manipulating single engrams, little is known about how …

Highlights•We review the history of research into putative memory storage mechanisms.•We
highlight recent advances catalyzed by memory engram labeling technology.•We discuss …

Over the past half-century, we have gained significant insights into the molecular biology of
long-term memory storage at the level of the synapse. In recent years, our understanding of …

Educational practice does not, for the most part, rely on research findings. Instead, there'sa
preference for relying on our intuitions about what's best for learning. But relying on intuition …

The formation and retrieval of a memory is thought to be accomplished by activation and
reactivation, respectively, of the memory-holding cells (engram cells) by a common set of …