[HTML][HTML] Synaptic plasticity, engrams, and network oscillations in amygdala circuits for storage and retrieval of emotional memories

M Bocchio, S Nabavi, M Capogna - Neuron, 2017 - cell.com
The neuronal circuits of the basolateral amygdala (BLA) are crucial for acquisition,
consolidation, retrieval, and extinction of associative emotional memories. Synaptic plasticity …

The hippocampal engram maps experience but not place

KZ Tanaka, H He, A Tomar, K Niisato, AJY Huang… - Science, 2018 - science.org
Episodic memories are encoded by a sparse population of hippocampal neurons. In mice,
optogenetic manipulation of this memory engram established that these neurons are …

[HTML][HTML] The brain in motion: How ensemble fluidity drives memory-updating and flexibility

W Mau, ME Hasselmo, DJ Cai - Elife, 2020 - elifesciences.org
While memories are often thought of as flashbacks to a previous experience, they do not
simply conserve veridical representations of the past but must continually integrate new …

[HTML][HTML] Amygdala reward neurons form and store fear extinction memory

X Zhang, J Kim, S Tonegawa - Neuron, 2020 - cell.com
The ability to extinguish conditioned fear memory is critical for adaptive control of fear
response, and its impairment is a hallmark of emotional disorders like post-traumatic stress …

Locus coeruleus input to hippocampal CA3 drives single-trial learning of a novel context

A Wagatsuma, T Okuyama, C Sun… - Proceedings of the …, 2018 - National Acad Sciences
The memory for a new episode is formed immediately upon experience and can last up to a
lifetime. It has been shown that the hippocampal network plays a fundamental role in the …

[HTML][HTML] Cytoelectric coupling: Electric fields sculpt neural activity and “tune” the brain's infrastructure

DA Pinotsis, G Fridman, EK Miller - Progress in Neurobiology, 2023 - Elsevier
We propose and present converging evidence for the Cytoelectric Coupling Hypothesis:
Electric fields generated by neurons are causal down to the level of the cytoskeleton. This …

[HTML][HTML] Functionally distinct neuronal ensembles within the memory engram

X Sun, MJ Bernstein, M Meng, S Rao, AT Sørensen… - Cell, 2020 - cell.com
Memories are believed to be encoded by sparse ensembles of neurons in the brain.
However, it remains unclear whether there is functional heterogeneity within individual …

[HTML][HTML] Engram cell excitability state determines the efficacy of memory retrieval

M Pignatelli, TJ Ryan, DS Roy, C Lovett, LM Smith… - Neuron, 2019 - cell.com
Animals need to optimize the efficacy of memory retrieval to adapt to environmental
circumstances for survival. The recent development of memory engram labeling technology …

[HTML][HTML] Intrusive memories of trauma: A target for research bridging cognitive science and its clinical application

L Iyadurai, RM Visser, A Lau-Zhu, K Porcheret… - Clinical psychology …, 2019 - Elsevier
Intrusive memories of a traumatic event can be distressing and disruptive, and comprise a
core clinical feature of post-traumatic stress disorder (PTSD). Intrusive memories involve …

[HTML][HTML] Dopaminergic neurons write and update memories with cell-type-specific rules

Y Aso, GM Rubin - Elife, 2016 - elifesciences.org
Associative learning is thought to involve parallel and distributed mechanisms of memory
formation and storage. In Drosophila, the mushroom body (MB) is the major site of …