[HTML][HTML] Synaptic plasticity, engrams, and network oscillations in amygdala circuits for storage and retrieval of emotional memories
The neuronal circuits of the basolateral amygdala (BLA) are crucial for acquisition,
consolidation, retrieval, and extinction of associative emotional memories. Synaptic plasticity …
consolidation, retrieval, and extinction of associative emotional memories. Synaptic plasticity …
The hippocampal engram maps experience but not place
Episodic memories are encoded by a sparse population of hippocampal neurons. In mice,
optogenetic manipulation of this memory engram established that these neurons are …
optogenetic manipulation of this memory engram established that these neurons are …
[HTML][HTML] The brain in motion: How ensemble fluidity drives memory-updating and flexibility
W Mau, ME Hasselmo, DJ Cai - Elife, 2020 - elifesciences.org
While memories are often thought of as flashbacks to a previous experience, they do not
simply conserve veridical representations of the past but must continually integrate new …
simply conserve veridical representations of the past but must continually integrate new …
[HTML][HTML] Amygdala reward neurons form and store fear extinction memory
X Zhang, J Kim, S Tonegawa - Neuron, 2020 - cell.com
The ability to extinguish conditioned fear memory is critical for adaptive control of fear
response, and its impairment is a hallmark of emotional disorders like post-traumatic stress …
response, and its impairment is a hallmark of emotional disorders like post-traumatic stress …
Locus coeruleus input to hippocampal CA3 drives single-trial learning of a novel context
The memory for a new episode is formed immediately upon experience and can last up to a
lifetime. It has been shown that the hippocampal network plays a fundamental role in the …
lifetime. It has been shown that the hippocampal network plays a fundamental role in the …
[HTML][HTML] Cytoelectric coupling: Electric fields sculpt neural activity and “tune” the brain's infrastructure
We propose and present converging evidence for the Cytoelectric Coupling Hypothesis:
Electric fields generated by neurons are causal down to the level of the cytoskeleton. This …
Electric fields generated by neurons are causal down to the level of the cytoskeleton. This …
[HTML][HTML] Functionally distinct neuronal ensembles within the memory engram
Memories are believed to be encoded by sparse ensembles of neurons in the brain.
However, it remains unclear whether there is functional heterogeneity within individual …
However, it remains unclear whether there is functional heterogeneity within individual …
[HTML][HTML] Engram cell excitability state determines the efficacy of memory retrieval
Animals need to optimize the efficacy of memory retrieval to adapt to environmental
circumstances for survival. The recent development of memory engram labeling technology …
circumstances for survival. The recent development of memory engram labeling technology …
[HTML][HTML] Intrusive memories of trauma: A target for research bridging cognitive science and its clinical application
Intrusive memories of a traumatic event can be distressing and disruptive, and comprise a
core clinical feature of post-traumatic stress disorder (PTSD). Intrusive memories involve …
core clinical feature of post-traumatic stress disorder (PTSD). Intrusive memories involve …
[HTML][HTML] Dopaminergic neurons write and update memories with cell-type-specific rules
Associative learning is thought to involve parallel and distributed mechanisms of memory
formation and storage. In Drosophila, the mushroom body (MB) is the major site of …
formation and storage. In Drosophila, the mushroom body (MB) is the major site of …