Simple Summary Cancer stem cells (CSCs) fuel tumor growth, metastasis and resistance to
therapy in colorectal cancer (CRC). These cells therefore represent a promising target for …

Colorectal cancer, a leading cause of mortality worldwide, is a multistep disorder that results
from the alteration of genetic and epigenetic mechanisms under contextual influence …

Tumor recurrence following treatment remains a major clinical challenge. Evidence from
xenograft models and human trials indicates selective enrichment of cancer-initiating cells …

SOX9 [sex-determining region Y (SRY)-box 9 protein], a high mobility group box
transcription factor, plays critical roles during embryogenesis and its activity is required for …

The acquisition of stemness in colorectal cancer (CRC) attributed to the recurrence and
metastasis in CRC treatment. Therefore, targeting the stemness of CRC forms a basis for the …

Tumor recurrence following treatment remains a major clinical challenge in oral cavity
cancer. Cancer stem cells (CSCs) have been isolated from human oral cancers and been …

Colon cancer is one of the leading causes of cancer-related deaths worldwide, despite
recent advances in clinical oncology. Accumulating evidence sheds light on the existence of …

Colorectal cancer (CRC) is the third most common cancer diagnosed worldwide and is
heterogeneous both morphologically and molecularly. In an era of personalized medicine …

Numerous changes in epigenetic mechanisms have been described in various types of
tumors. In search for new biomarkers, we investigated the expression of Polycomb-group …

Colorectal cancer is the third-leading cause of cancer related mortality in the United States.
The intricate molecular mechanisms involved in the regenerative process of the normal …