Impact of alternative splicing variants on liver cancer biology
Simple Summary Among the top ten deadly solid tumors are the two most frequent liver
cancers, hepatocellular carcinoma, and intrahepatic cholangiocarcinoma, whose …
cancers, hepatocellular carcinoma, and intrahepatic cholangiocarcinoma, whose …
[HTML][HTML] Alternative splicing and liver disease
M Baralle, FE Baralle - Annals of hepatology, 2021 - Elsevier
Alternative splicing produces complex and dynamic changes in the protein isoforms that are
necessary for the proper biological functioning of the metabolic pathways involved in liver …
necessary for the proper biological functioning of the metabolic pathways involved in liver …
Dysregulation of RNA splicing in early non-alcoholic fatty liver disease through hepatocellular carcinoma
While changes in RNA splicing have been extensively studied in hepatocellular carcinoma
(HCC), no studies have systematically investigated changes in RNA splicing during earlier …
(HCC), no studies have systematically investigated changes in RNA splicing during earlier …
Hepatocyte deletion of IGF2 prevents DNA damage and tumor formation in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Serine‐
arginine rich splicing factor 3 (SRSF3) plays a critical role in hepatocyte function and its loss …
arginine rich splicing factor 3 (SRSF3) plays a critical role in hepatocyte function and its loss …
Immunological significance of prognostic alternative splicing signature in hepatocellular carcinoma
Q Xu, H Xu, R Deng, N Li, R Mu, Z Qi, Y Shen… - Cancer cell …, 2021 - Springer
Background Hepatocellular carcinoma (HCC) ranks the sixth prevalent tumors with high
mortality globally. Alternative splicing (AS) drives protein diversity, the imbalance of which …
mortality globally. Alternative splicing (AS) drives protein diversity, the imbalance of which …
Identification of drug targets and prognosis projection for uterine carcinosarcoma based on alternative splicing events
X Zhang, X Yin, L Zhang, Z Ye, G Liang - Computers in Biology and …, 2023 - Elsevier
Background Uterine carcinosarcoma (UCS) is an invasive variant of endometrial cancer.
The complicated heterogeneity and low frequency of UCS suggest the relevant research is …
The complicated heterogeneity and low frequency of UCS suggest the relevant research is …
Decoding the role of aberrant RNA alternative splicing in hepatocellular carcinoma: a comprehensive review
M Sheng, Y Zhang, Y Wang, W Liu, X Wang… - Journal of Cancer …, 2023 - Springer
During eukaryotic gene expression, alternative splicing of messenger RNA precursors is
critical in increasing protein diversity and regulatory complexity. Multiple transcript isoforms …
critical in increasing protein diversity and regulatory complexity. Multiple transcript isoforms …
A systems biology‐based approach to screen key splicing factors in hepatocellular carcinoma
R Zhu, X Wang, Q Yu, W Guo… - Molecular Carcinogenesis, 2023 - Wiley Online Library
A splicing factor is as an important upstream regulator of the alternative splicing process.
Hence, it is considered to be a therapeutic target for hepatocellular carcinoma (HCC) …
Hence, it is considered to be a therapeutic target for hepatocellular carcinoma (HCC) …
[HTML][HTML] Identification of prognostic alternative splicing signatures in hepatitis B or/and C viruses related hepatocellular carcinoma
Y Cai, J Xia, N Wang, H Zhou - Genomics, 2020 - Elsevier
Background Alternative splicing (AS) takes a crucial part in tumor process. We aim to
analyze AS in Hepatitis B virus (HBV) or/and hepatitis C virus (HCV) related hepatocellular …
analyze AS in Hepatitis B virus (HBV) or/and hepatitis C virus (HCV) related hepatocellular …
Aberrant RNA splicing events driven by mutations of RNA-binding proteins as indicators for skin cutaneous melanoma prognosis
C Mei, PY Song, W Zhang, HH Zhou, X Li… - Frontiers in …, 2020 - frontiersin.org
The worldwide incidence of skin cutaneous melanoma (SKCM) is increasing at a more rapid
rate than other tumors. Aberrant alternative splicing (AS) is found to be common in cancer; …
rate than other tumors. Aberrant alternative splicing (AS) is found to be common in cancer; …