Clinical biology of the pituitary adenoma

S Melmed, UB Kaiser, MB Lopes, J Bertherat… - Endocrine …, 2022 - academic.oup.com
All endocrine glands are susceptible to neoplastic growth, yet the health consequences of
these neoplasms differ between endocrine tissues. Pituitary neoplasms are highly prevalent …

Multidisciplinary management of acromegaly: a consensus

A Giustina, G Barkhoudarian, A Beckers… - Reviews in Endocrine …, 2020 - Springer
Abstract The 13th Acromegaly Consensus Conference was held in November 2019 in Fort
Lauderdale, Florida, and comprised acromegaly experts including endocrinologists and …

[HTML][HTML] A Pituitary Society update to acromegaly management guidelines

M Fleseriu, BMK Biller, PU Freda, MR Gadelha… - Pituitary, 2021 - Springer
Guidelines and consensus statements ensure that physicians managing acromegaly
patients have access to current information on evidence-based treatments to optimize …

A consensus on the diagnosis and treatment of acromegaly comorbidities: an update

A Giustina, A Barkan, A Beckers… - The Journal of …, 2020 - academic.oup.com
Objective The aim of the Acromegaly Consensus Group was to revise and update the
consensus on diagnosis and treatment of acromegaly comorbidities last published in 2013 …

Acromegaly: pathogenesis, diagnosis, and management

M Fleseriu, F Langlois, DST Lim… - The Lancet Diabetes & …, 2022 - thelancet.com
Growth hormone-secreting pituitary adenomas that cause acromegaly arise as monoclonal
expansions of differentiated somatotroph cells and are usually sporadic. They are almost …

[HTML][HTML] Insulin-like growth factor 1 (IGF-1) signaling in glucose metabolism in colorectal cancer

A Kasprzak - International journal of molecular sciences, 2021 - mdpi.com
Colorectal cancer (CRC) is one of the most common aggressive carcinoma types worldwide,
characterized by unfavorable curative effect and poor prognosis. Epidemiological data re …

New horizons: novel approaches to enhance healthspan through targeting cellular senescence and related aging mechanisms

T Tchkonia, AK Palmer… - The Journal of Clinical …, 2021 - academic.oup.com
The elderly population is increasing faster than other segments of the population throughout
the world. Age is the leading predictor for most chronic diseases and disorders …

[HTML][HTML] Consensus on criteria for acromegaly diagnosis and remission

A Giustina, N Biermasz, FF Casanueva, M Fleseriu… - Pituitary, 2024 - Springer
Abstract Purpose The 14th Acromegaly Consensus Conference was convened to consider
biochemical criteria for acromegaly diagnosis and evaluation of therapeutic efficacy …

Acromegaly

S Melmed - The pituitary, 2017 - Elsevier
Acromegaly is caused by excess growth hormone (GH) secretion emanating from a
somatotroph adenoma. High GH and Insulin-like growth factor-1 (IGF-1) levels lead to acral …

Maintenance of acromegaly control in patients switching from injectable somatostatin receptor ligands to oral octreotide

SL Samson, LB Nachtigall, M Fleseriu… - The Journal of …, 2020 - academic.oup.com
Abstract Purpose The phase 3 CHIASMA OPTIMAL trial (NCT03252353) evaluated efficacy
and safety of oral octreotide capsules (OOCs) in patients with acromegaly who previously …