Raman spectroscopy for chemical biology research
In chemical biology research, various fluorescent probes have been developed and used to
visualize target proteins or molecules in living cells and tissues, yet there are limitations to …
visualize target proteins or molecules in living cells and tissues, yet there are limitations to …
The emerging role of Raman spectroscopy as an omics approach for metabolic profiling and biomarker detection toward precision medicine
G Cutshaw, S Uthaman, N Hassan… - Chemical …, 2023 - ACS Publications
Omics technologies have rapidly evolved with the unprecedented potential to shape
precision medicine. Novel omics approaches are imperative toallow rapid and accurate data …
precision medicine. Novel omics approaches are imperative toallow rapid and accurate data …
Biological imaging of chemical bonds by stimulated Raman scattering microscopy
All molecules consist of chemical bonds, and much can be learned from mapping the
spatiotemporal dynamics of these bonds. Since its invention a decade ago, stimulated …
spatiotemporal dynamics of these bonds. Since its invention a decade ago, stimulated …
Instant diagnosis of gastroscopic biopsy via deep-learned single-shot femtosecond stimulated Raman histology
Gastroscopic biopsy provides the only effective method for gastric cancer diagnosis, but the
gold standard histopathology is time-consuming and incompatible with gastroscopy …
gold standard histopathology is time-consuming and incompatible with gastroscopy …
Recent insights into the function of autophagy in cancer
R Amaravadi, AC Kimmelman, E White - Genes & development, 2016 - genesdev.cshlp.org
Macroautophagy (referred to here as autophagy) is induced by starvation to capture and
degrade intracellular proteins and organelles in lysosomes, which recycles intracellular …
degrade intracellular proteins and organelles in lysosomes, which recycles intracellular …
Vibrational spectroscopic imaging of living systems: An emerging platform for biology and medicine
BACKGROUND Biomolecules can serve as natural labels for microscopy by measuring their
molecular vibration spectra in living cells and tissues. However, the transition from …
molecular vibration spectra in living cells and tissues. However, the transition from …
Targeting autophagy in cancer: update on clinical trials and novel inhibitors
CI Chude, RK Amaravadi - International journal of molecular sciences, 2017 - mdpi.com
Eukaryotes use autophagy as a mechanism for maintaining cellular homeostasis by
degrading and recycling organelles and proteins. This process assists in the proliferation …
degrading and recycling organelles and proteins. This process assists in the proliferation …
Raman spectroscopy: techniques and applications in the life sciences
Raman spectroscopy is an increasingly popular technique in many areas, including biology
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …
New modalities for challenging targets in drug discovery
E Valeur, SM Guéret, H Adihou… - Angewandte Chemie …, 2017 - Wiley Online Library
Our ever‐increasing understanding of biological systems is providing a range of exciting
novel biological targets, whose modulation may enable novel therapeutic options for many …
novel biological targets, whose modulation may enable novel therapeutic options for many …
Determination of the subcellular localization and mechanism of action of ferrostatins in suppressing ferroptosis
Ferroptosis is a form of nonapoptotic cell death characterized by the unchecked
accumulation of lipid peroxides. Ferrostatin-1 and its analogs (ferrostatins) specifically …
accumulation of lipid peroxides. Ferrostatin-1 and its analogs (ferrostatins) specifically …