[HTML][HTML] Multidrug resistance (MDR): A widespread phenomenon in pharmacological therapies
A Catalano, D Iacopetta, J Ceramella, D Scumaci… - Molecules, 2022 - mdpi.com
Multidrug resistance is a leading concern in public health. It describes a complex phenotype
whose predominant feature is resistance to a wide range of structurally unrelated cytotoxic …
whose predominant feature is resistance to a wide range of structurally unrelated cytotoxic …
[HTML][HTML] Multidrug resistance in mammals and fungi—From MDR to PDR: A rocky road from atomic structures to transport mechanisms
N Khunweeraphong, K Kuchler - International Journal of Molecular …, 2021 - mdpi.com
Multidrug resistance (MDR) can be a serious complication for the treatment of cancer as well
as for microbial and parasitic infections. Dysregulated overexpression of several members of …
as for microbial and parasitic infections. Dysregulated overexpression of several members of …
Insights into integrated glycerol-driven partial denitrification-anaerobic ammonium oxidation system using bioinformatic analysis: The dominance of Bacillus spp. and …
T Zhang, J Cao, W Liu, G Liu, C Huang, J Luo - Science of The Total …, 2023 - Elsevier
Partial denitrification-anaerobic ammonium oxidation (PD/A) was considered a novel
technology for biological nitrogen removal. In this study, a glycerol-driven PD/A granular …
technology for biological nitrogen removal. In this study, a glycerol-driven PD/A granular …
[HTML][HTML] Impaired biosynthesis of ergosterol confers resistance to complex sphingolipid biosynthesis inhibitor aureobasidin A in a PDR16-dependent manner
S Fukuda, Y Kono, Y Ishibashi, M Tabuchi, M Tani - Scientific reports, 2023 - nature.com
Complex sphingolipids and sterols are coordinately involved in various cellular functions, eg
the formation of lipid microdomains. Here we found that budding yeast exhibits resistance to …
the formation of lipid microdomains. Here we found that budding yeast exhibits resistance to …
[HTML][HTML] Botrytis cinerea tolerates phytoalexins produced by Solanaceae and Fabaceae plants through an efflux transporter BcatrB and metabolizing enzymes
AS Bulasag, M Camagna, T Kuroyanagi… - Frontiers in Plant …, 2023 - frontiersin.org
Botrytis cinerea, a plant pathogenic fungus with a wide host range, has reduced sensitivity to
fungicides as well as phytoalexins, threatening cultivation of economically important fruits …
fungicides as well as phytoalexins, threatening cultivation of economically important fruits …
Transcriptomics and proteomics revealed the psychrotolerant and antibiotic-resistant mechanisms of strain Pseudomonas psychrophila RNC-1 capable of assimilatory …
Y Zhao, H Min, K Luo, R Zhang, Q Chen… - Science of The Total …, 2022 - Elsevier
Aerobic denitrification has been proved to be profoundly affected by temperature and
antibiotics, but little is known about how aerobic denitrifiers respond to temperature and …
antibiotics, but little is known about how aerobic denitrifiers respond to temperature and …
[HTML][HTML] Mechanisms of non-vesicular exchange of lipids at membrane contact sites: Of shuttles, tunnels and, funnels
PF Egea - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Eukaryotic cells are characterized by their exquisite compartmentalization resulting from a
cornucopia of membrane-bound organelles. Each of these compartments hosts a flurry of …
cornucopia of membrane-bound organelles. Each of these compartments hosts a flurry of …
Systematic analysis and comparison of ABC proteins superfamily confer structural, functional and evolutionary insights into four cotton species
WA Malik, M Afzal, X Chen, R Cui, X Lu, S Wang… - Industrial Crops and …, 2022 - Elsevier
Highlights•Most complex & extensive superfamily of transporters characterized by 2 (TMD-
NBDs).•ABCA-ABCF are highly conserved, while ABCG-ABCI are functionally advanced …
NBDs).•ABCA-ABCF are highly conserved, while ABCG-ABCI are functionally advanced …
Performance of high solids enzymatic hydrolysis and bioethanol fermentation of food waste under the regulation of saponin
H Zhou, J Jiang, Q Zhao, Z Wang, L Li, Q Gao… - Bioresource …, 2023 - Elsevier
Bioethanol recovery from food waste through high solids enzymatic hydrolysis (HSEH) and
high solids bioethanol fermentation (HSBF) alleviate the energy crisis. However, this cause …
high solids bioethanol fermentation (HSBF) alleviate the energy crisis. However, this cause …
[HTML][HTML] Cryptococcus neoformans adapts to the host environment through TOR-mediated remodeling of phospholipid asymmetry
Cryptococcus spp. are environmental fungi that first must adapt to the host environment
before they can cause life-threatening meningitis in immunocompromised patients. Host …
before they can cause life-threatening meningitis in immunocompromised patients. Host …