Glycyrrhizin: An alternative drug for the treatment of COVID-19 infection and the associated respiratory syndrome?

C Bailly, G Vergoten - Pharmacology & therapeutics, 2020 - Elsevier
Safe and efficient drugs to combat the current COVID-19 pandemic are urgently needed. In
this context, we have analyzed the anti-coronavirus potential of the natural product …

[HTML][HTML] Cholesterol-rich lipid rafts as platforms for SARS-CoV-2 entry

SN Palacios-Rapalo, LA De Jesus-Gonzalez… - Frontiers in …, 2021 - frontiersin.org
Since its appearance, the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2),
the causal agent of Coronavirus Disease 2019 (COVID-19), represents a global problem for …

[HTML][HTML] Association between antecedent statin use and decreased mortality in hospitalized patients with COVID-19

A Gupta, MV Madhavan, TJ Poterucha… - Nature …, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) can result in a hyperinflammatory state,
leading to acute respiratory distress syndrome (ARDS), myocardial injury, and thrombotic …

[HTML][HTML] Cholesterol in relation to COVID-19: should we care about it?

D Radenkovic, S Chawla, M Pirro, A Sahebkar… - Journal of clinical …, 2020 - mdpi.com
Current data suggest that infection with severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) causing corona virus disease-19 (COVID-19) seems to follow a more severe …

[HTML][HTML] Natural small molecules as inhibitors of coronavirus lipid-dependent attachment to host cells: a possible strategy for reducing SARS-COV-2 infectivity?

M Baglivo, M Baronio, G Natalini, T Beccari… - Acta Bio Medica …, 2020 - ncbi.nlm.nih.gov
Background: Viral infectivity depends on interactions between components of the host cell
plasma membrane and the virus envelope. Here we review strategies that could help stem …

[HTML][HTML] The role of high cholesterol in age-related COVID19 lethality.

H Wang, Z Yuan, MA Pavel, SM Jablonski, J Jablonski… - BioRxiv, 2020 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID19) is a respiratory infection caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) originating in Wuhan, China in …

[HTML][HTML] Cyclodextrins: Emerging medicines of the new millennium

SS Braga - Biomolecules, 2019 - mdpi.com
Cyclodextrins, since their discovery in the late 19th century, were mainly regarded as
excipients. Nevertheless, developments in cyclodextrin research have shown that some of …

[HTML][HTML] Membrane rafts: portals for viral entry

I Ripa, S Andreu, JA López-Guerrero… - Frontiers in …, 2021 - frontiersin.org
Membrane rafts are dynamic, small (10–200 nm) domains enriched with cholesterol and
sphingolipids that compartmentalize cellular processes. Rafts participate in roles essential to …

[HTML][HTML] SARS-CoV-2 evolutionary adaptation toward host entry and recognition of receptor O-Acetyl sialylation in virus–host interaction

CH Kim - International journal of molecular sciences, 2020 - mdpi.com
The recently emerged SARS-CoV-2 is the cause of the global health crisis of the coronavirus
disease 2019 (COVID-19) pandemic. No evidence is yet available for CoV infection into …

[HTML][HTML] Coronavirus infection and cholesterol metabolism

J Dai, H Wang, Y Liao, L Tan, Y Sun, C Song… - Frontiers in …, 2022 - frontiersin.org
Host cholesterol metabolism remodeling is significantly associated with the spread of human
pathogenic coronaviruses, suggesting virus-host relationships could be affected by …