[HTML][HTML] Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies

H Tian, T Zhang, S Qin, Z Huang, L Zhou, J Shi… - Journal of hematology & …, 2022 - Springer
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

[HTML][HTML] Luteolin as a potential hepatoprotective drug: Molecular mechanisms and treatment strategies

C Yao, S Dai, C Wang, K Fu, R Wu, X Zhao… - Biomedicine & …, 2023 - Elsevier
Luteolin is a flavonoid widely present in various traditional Chinese medicines. In recent
years, luteolin has received more attention due to its impressive liver protective effect, such …

[HTML][HTML] The role and mechanism of flavonoid herbal natural products in ulcerative colitis

JC Xue, S Yuan, H Meng, XT Hou, J Li… - Biomedicine & …, 2023 - Elsevier
Ulcerative colitis (UC) is a chronic inflammatory disease of the intestine that presents
clinically with abdominal pain, mucopurulent stools, and posterior urgency. The lesions of …

Self-homeostasis immunoregulatory strategy for implant-related infections through remodeling redox balance

D Xu, W Zhu, C Ding, J Mei, J Zhou, T Cheng, G Guo… - ACS …, 2023 - ACS Publications
Implant-related infections (IRIs) are catastrophic complications after orthopedic surgery.
Excess reactive oxygen species (ROS) accumulated in IRIs create a redox-imbalanced …

pH/ROS dual-sensitive natural polysaccharide nanoparticles enhance “one stone four birds” effect of rhein on ulcerative colitis

S Qi, R Luo, X Han, W Nie, N Ye, C Fu… - ACS Applied Materials & …, 2022 - ACS Publications
Rhein (RH), a natural anthraquinone compound, is considered an effective treatment
candidate for ulcerative colitis (UC), whose multiple biological activities contribute to UC …

Injectable bioadhesive hydrogels scavenging ROS and restoring mucosal barrier for enhanced ulcerative colitis therapy

D Li, J Li, T Chen, X Qin, L Pan, X Lin… - … Applied Materials & …, 2023 - ACS Publications
Despite the progress in the therapy of ulcerative colitis (UC), long-lasting UC remission can
hardly be achieved in the majority of UC patients. The key pathological characteristics of UC …

ROS responsive nanoparticles encapsulated with natural medicine remodel autophagy homeostasis in breast cancer

X Zhang, H Gao, D Wei, X Pei, Y Zhang… - … Applied Materials & …, 2023 - ACS Publications
In photodynamic therapy (PDT), elevated reactive oxygen species (ROS) activate tumor cell
protective autophagy, therefore attenuating the antitumor function of therapy. Hence …

[HTML][HTML] The progression of inorganic nanoparticles and natural products for inflammatory bowel disease

Q Li, L Lin, C Zhang, H Zhang, Y Ma, H Qian… - Journal of …, 2024 - Springer
There is a growing body of evidence indicating a close association between inflammatory
bowel disease (IBD) and disrupted intestinal homeostasis. Excessive production of reactive …

Oral delivery of porous starch-loaded bilayer microgels for controlled drug delivery and treatment of ulcerative colitis

Z Wen, L Kang, H Fu, S Zhu, X Ye, X Yang… - Carbohydrate …, 2023 - Elsevier
We prepared one type of bilayer microgels for oral administration with three effects: pH
responsiveness, time lag, and colon enzyme degradation. Combined with the dual …

Nanomedicine for T‐Cell Mediated Immunotherapy

F Li, J Ouyang, Z Chen, Z Zhou… - Advanced …, 2024 - Wiley Online Library
T‐cell immunotherapy offers outstanding advantages in the treatment of various diseases,
and with the selection of appropriate targets, efficient disease treatment can be achieved. T …