[HTML][HTML] Genetics of human social behavior
Human beings are an incredibly social species and along with eusocial insects engage in
the largest cooperative living groups in the planet's history. Twin and family studies suggest …
the largest cooperative living groups in the planet's history. Twin and family studies suggest …
[HTML][HTML] Genome-wide association studies in ADHD
Attention-deficit/hyperactivity disorder, ADHD, is a common and highly heritable
neuropsychiatric disorder that is seen in children and adults. Although heritability is …
neuropsychiatric disorder that is seen in children and adults. Although heritability is …
Practical aspects of imputation-driven meta-analysis of genome-wide association studies
Motivated by the overwhelming success of genome-wide association studies, droves of
researchers are working vigorously to exchange and to combine genetic data to expediently …
researchers are working vigorously to exchange and to combine genetic data to expediently …
Twin studies in autoimmune disease: genetics, gender and environment
DP Bogdanos, DS Smyk, EI Rigopoulou… - Journal of …, 2012 - Elsevier
Twin studies are powerful tools to discriminate whether a complex disease is due to genetic
or environmental factors. High concordance rates among monozygotic (MZ) twins support …
or environmental factors. High concordance rates among monozygotic (MZ) twins support …
[HTML][HTML] Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease
Background With the exception of APOE ε4 allele, the common genetic risk factors for
sporadic Alzheimer's Disease (AD) are unknown. Methods and Findings We completed a …
sporadic Alzheimer's Disease (AD) are unknown. Methods and Findings We completed a …
[HTML][HTML] The psychiatric GWAS consortium: big science comes to psychiatry
PF Sullivan - Neuron, 2010 - cell.com
The Psychiatric GWAS Consortium was founded with the aim of conducting statistically
rigorous and comprehensive GWAS meta-analyses for five major psychiatric disorders …
rigorous and comprehensive GWAS meta-analyses for five major psychiatric disorders …
[HTML][HTML] Methylation at SLC6A4 is linked to family history of child abuse: an examination of the Iowa Adoptee sample
In this letter we describe novel, preliminary work, examining a possible mechanism of the
Gene-environment interactions thought to moderate the response of individuals to stressful …
Gene-environment interactions thought to moderate the response of individuals to stressful …
Phenopedia and Genopedia: disease-centered and gene-centered views of the evolving knowledge of human genetic associations
We developed web-based applications that encourage the exploration of the literature on
human genetic associations by using a database that is continuously updated from PubMed …
human genetic associations by using a database that is continuously updated from PubMed …
Genetic modifiers of ambulation in the cooperative international Neuromuscular research group Duchenne natural history study
L Bello, A Kesari, H Gordish‐Dressman… - Annals of …, 2015 - Wiley Online Library
Objective We studied the effects of LTBP4 and SPP1 polymorphisms on age at loss of
ambulation (LoA) in a multiethnic Duchenne muscular dystrophy (DMD) cohort. Methods We …
ambulation (LoA) in a multiethnic Duchenne muscular dystrophy (DMD) cohort. Methods We …
Quality control for genome-wide association studies
ME Weale - Genetic variation: methods and protocols, 2010 - Springer
This chapter is a comprehensive review of quality control (QC) methods for SNP-based
genotyping panels used in genome-wide association studies. These include QC on …
genotyping panels used in genome-wide association studies. These include QC on …