[HTML][HTML] Cardiac transmembrane ion channels and action potentials: cellular physiology and arrhythmogenic behavior
Cardiac arrhythmias are among the leading causes of mortality. They often arise from
alterations in the electrophysiological properties of cardiac cells and their underlying ionic …
alterations in the electrophysiological properties of cardiac cells and their underlying ionic …
Precision medicine in human heart modeling: perspectives, challenges, and opportunities
Precision medicine is a new frontier in healthcare that uses scientific methods to customize
medical treatment to the individual genes, anatomy, physiology, and lifestyle of each person …
medical treatment to the individual genes, anatomy, physiology, and lifestyle of each person …
A survey on digital twin: Definitions, characteristics, applications, and design implications
When, in 1956, Artificial Intelligence (AI) was officially declared a research field, no one
would have ever predicted the huge influence and impact its description, prediction, and …
would have ever predicted the huge influence and impact its description, prediction, and …
[HTML][HTML] A comprehensive and biophysically detailed computational model of the whole human heart electromechanics
While ventricular electromechanics is extensively studied in both physiological and
pathological conditions, four-chamber heart models have only been addressed recently; …
pathological conditions, four-chamber heart models have only been addressed recently; …
A review of inflammatory mechanism in airway diseases
P Aghasafari, U George, R Pidaparti - Inflammation Research, 2019 - Springer
Background Inflammation in the lung is the body's natural response to injury. It acts to
remove harmful stimuli such as pathogens, irritants, and damaged cells and initiate the …
remove harmful stimuli such as pathogens, irritants, and damaged cells and initiate the …
A novel rule-based algorithm for assigning myocardial fiber orientation to computational heart models
Electrical waves traveling throughout the myocardium elicit muscle contractions responsible
for pumping blood throughout the body. The shape and direction of these waves depend on …
for pumping blood throughout the body. The shape and direction of these waves depend on …
A mathematical model that integrates cardiac electrophysiology, mechanics, and fluid dynamics: Application to the human left heart
We propose a mathematical and numerical model for the simulation of the heart function that
couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and …
couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and …
Integrated heart—coupling multiscale and multiphysics models for the simulation of the cardiac function
Mathematical modeling of the human heart and its function can expand our understanding of
various cardiac diseases, which remain the most common cause of death in the developed …
various cardiac diseases, which remain the most common cause of death in the developed …
[HTML][HTML] The living heart project: a robust and integrative simulator for human heart function
B Baillargeon, N Rebelo, DD Fox, RL Taylor… - European Journal of …, 2014 - Elsevier
The heart is not only our most vital, but also our most complex organ: Precisely controlled by
the interplay of electrical and mechanical fields, it consists of four chambers and four valves …
the interplay of electrical and mechanical fields, it consists of four chambers and four valves …
Modeling cardiac muscle fibers in ventricular and atrial electrophysiology simulations
Since myocardial fibers drive the electric signal propagation throughout the myocardium,
accurately modeling their arrangement is essential for simulating heart electrophysiology …
accurately modeling their arrangement is essential for simulating heart electrophysiology …