Assessment and pathophysiology of microvascular disease: recent progress and clinical implications
The development of novel, non-invasive techniques and standardization of protocols to
assess microvascular dysfunction have elucidated the key role of microvascular changes in …
assess microvascular dysfunction have elucidated the key role of microvascular changes in …
Immune system and microvascular remodeling in humans
Low-grade inflammatory processes and related oxidative stress may have a key role in the
pathogenesis of hypertension and hypertension-mediated organ damage. Innate immune …
pathogenesis of hypertension and hypertension-mediated organ damage. Innate immune …
Targeting SIRT1 rescues age-and obesity-induced microvascular dysfunction in ex vivo human vessels
Background: Experimental evidence suggests a key role of SIRT1 (silent information
regulator 1) in age-and metabolic-related vascular dysfunction. Whether these effects hold …
regulator 1) in age-and metabolic-related vascular dysfunction. Whether these effects hold …
New noninvasive methods to evaluate microvascular structure and function
The structural and functional alterations of microvessels are detected because of
physiological aging and in several cardiometabolic diseases, including hypertension …
physiological aging and in several cardiometabolic diseases, including hypertension …
Sympathetic nervous system and hypertension: New evidences
G Seravalle, G Grassi - Autonomic Neuroscience, 2022 - Elsevier
Evidences collected in the past few years have strengthened the concept that the
sympathetic nervous system plays a primary role in the development and progression of the …
sympathetic nervous system plays a primary role in the development and progression of the …
Oxidative stress in arterial hypertension (HTN): The nuclear factor erythroid factor 2-related factor 2 (Nrf2) pathway, implications and future perspectives
Arterial hypertension (HTN) is one of the most prevalent entities globally, characterized by
increased incidence and heterogeneous pathophysiology. Among possible etiologies …
increased incidence and heterogeneous pathophysiology. Among possible etiologies …
New Insights into Endothelial Dysfunction in Cardiometabolic Diseases: Potential Mechanisms and Clinical Implications
The endothelium is a monocellular layer covering the inner surface of blood vessels. It
maintains vascular homeostasis regulating vascular tone and permeability and exerts anti …
maintains vascular homeostasis regulating vascular tone and permeability and exerts anti …
Microvascular ageing links metabolic disease to age-related disorders: the role of oxidative stress and inflammation in promoting microvascular dysfunction
A Mengozzi, NR Pugliese, M Chiriacò… - Journal of …, 2021 - journals.lww.com
Longer life span and increased prevalence of chronic, noncommunicable, inflammatory
diseases fuel cardiovascular mortality. The microcirculation is central in the cross talk …
diseases fuel cardiovascular mortality. The microcirculation is central in the cross talk …
Microcirculation in hypertension: a therapeutic target to prevent cardiovascular disease?
Arterial hypertension is a common condition worldwide and an important risk factor for
cardio-and cerebrovascular events, renal diseases, as well as microvascular eye diseases …
cardio-and cerebrovascular events, renal diseases, as well as microvascular eye diseases …
Ubiquinol ameliorates endothelial dysfunction in subjects with mild-to-moderate dyslipidemia: a randomized clinical trial
J Sabbatinelli, P Orlando, R Galeazzi, S Silvestri… - Nutrients, 2020 - mdpi.com
In this randomized, double-blind, single-center trial (ANZCTR number
ACTRN12619000436178) we aimed to investigate changes in endothelium-dependent …
ACTRN12619000436178) we aimed to investigate changes in endothelium-dependent …