[HTML][HTML] Glucocorticosteroid therapy in inflammatory bowel diseases: From clinical practice to molecular biology
K Dubois-Camacho, PA Ottum… - World journal of …, 2017 - ncbi.nlm.nih.gov
Inflammatory bowel diseases (IBDs), such as ulcerative colitis and Crohn's disease, are
chronic pathologies associated with a deregulated immune response in the intestinal …
chronic pathologies associated with a deregulated immune response in the intestinal …
Decoding IL-23 signaling cascade for new therapeutic opportunities
G Pastor-Fernández, IR Mariblanca, MN Navarro - Cells, 2020 - mdpi.com
The interleukin 23 (IL-23) is a key pro-inflammatory cytokine in the development of chronic
inflammatory diseases, such as psoriasis, inflammatory bowel diseases, multiple sclerosis …
inflammatory diseases, such as psoriasis, inflammatory bowel diseases, multiple sclerosis …
Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon Carcinogenesis
AL Geis, H Fan, X Wu, S Wu, DL Huso, JL Wolfe… - Cancer discovery, 2015 - AACR
Many epithelial cancers are associated with chronic inflammation. However, the features of
inflammation that are procarcinogenic are not fully understood. Regulatory T cells (Treg) …
inflammation that are procarcinogenic are not fully understood. Regulatory T cells (Treg) …
Genetic epidemiology of psoriasis
R Gupta, MG Debbaneh, W Liao - Current dermatology reports, 2014 - Springer
Psoriasis is a chronic, inflammatory, immune-mediated skin condition with a prevalence of 0–
11.8% across the world. It is associated with a number of cardiovascular, metabolic, and …
11.8% across the world. It is associated with a number of cardiovascular, metabolic, and …
Meta-analysis derived (MAD) transcriptome of psoriasis defines the “core” pathogenesis of disease
S Tian, JG Krueger, K Li, A Jabbari, C Brodmerkel… - 2012 - journals.plos.org
The cause of psoriasis, a common chronic inflammatory skin disease, is not fully understood.
Microarray experiments have been widely used in recent years to identify genes associated …
Microarray experiments have been widely used in recent years to identify genes associated …
Lessons learned from trials targeting cytokine pathways in patients with inflammatory bowel diseases
C Abraham, PS Dulai, S Vermeire, WJ Sandborn - Gastroenterology, 2017 - Elsevier
Insights into the pathogenesis of inflammatory bowel diseases (IBDs) have provided
important information for the development of therapeutics. Levels of interleukin 23 (IL23) and …
important information for the development of therapeutics. Levels of interleukin 23 (IL23) and …
Insights into IL-23 biology: from structure to function
Abstract Interleukin (IL-) 23 is a central cytokine controlling TH 17 development.
Overshooting IL-23 signaling contribute to autoimmune diseases. Moreover, GWAS studies …
Overshooting IL-23 signaling contribute to autoimmune diseases. Moreover, GWAS studies …
Anti-TNF therapy in spondyloarthritis and related diseases, impact on the immune system and prediction of treatment responses
S Menegatti, E Bianchi, L Rogge - Frontiers in immunology, 2019 - frontiersin.org
Immune-mediated inflammatory diseases (IMIDs), such as spondyloarthritis (SpA), psoriasis,
Crohn's disease (CD), and rheumatoid arthritis (RA) remain challenging illnesses. They …
Crohn's disease (CD), and rheumatoid arthritis (RA) remain challenging illnesses. They …
Genetics of ankylosing spondylitis
PC Robinson, MA Brown - Molecular immunology, 2014 - Elsevier
Ankylosing spondylitis (AS) is a chronic inflammatory arthritis that affects the spine and
sacroiliac joints. It causes significant disability and is associated with a number of other …
sacroiliac joints. It causes significant disability and is associated with a number of other …
Tumor necrosis factor-α inhibitor-related autoimmune disorders
L De Stefano, FB Pallavicini, E Mauric, V Piccin… - Autoimmunity …, 2023 - Elsevier
Biotechnological monoclonal antibodies and receptor antagonists capable of targeting
specific inflammatory actors, such as cytokines, cytokines receptors, co-stimulatory …
specific inflammatory actors, such as cytokines, cytokines receptors, co-stimulatory …