Antibiotic perturbations to the gut microbiome
Antibiotic-mediated perturbation of the gut microbiome is associated with numerous
infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome …
infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome …
Examining horizontal gene transfer in microbial communities
IL Brito - Nature Reviews Microbiology, 2021 - nature.com
Bacteria acquire novel DNA through horizontal gene transfer (HGT), a process that enables
an organism to rapidly adapt to changing environmental conditions, provides a competitive …
an organism to rapidly adapt to changing environmental conditions, provides a competitive …
Understanding the impact of antibiotic perturbation on the human microbiome
The human gut microbiome is a dynamic collection of bacteria, archaea, fungi, and viruses
that performs essential functions for immune development, pathogen colonization …
that performs essential functions for immune development, pathogen colonization …
Gut microbiome dysbiosis is associated with increased mortality after solid organ transplantation
Organ transplantation is a life-saving treatment for patients with end-stage disease, but
survival rates after transplantation vary considerably. There is now increasing evidence that …
survival rates after transplantation vary considerably. There is now increasing evidence that …
[HTML][HTML] Antibiotic resistance in the commensal human gut microbiota
LE Lamberte, W van Schaik - Current Opinion in Microbiology, 2022 - Elsevier
Highlights•The human gut microbiota serves as a reservoir of antibiotic resistance
genes.•DNA sequencing and culture techniques are used to characterise the gut …
genes.•DNA sequencing and culture techniques are used to characterise the gut …
Widespread transfer of mobile antibiotic resistance genes within individual gut microbiomes revealed through bacterial Hi-C
The gut microbiome harbors a 'silent reservoir'of antibiotic resistance (AR) genes that is
thought to contribute to the emergence of multidrug-resistant pathogens through horizontal …
thought to contribute to the emergence of multidrug-resistant pathogens through horizontal …
Effects of antibiotic treatment on gut microbiota and how to overcome its negative impacts on human health
CFA Ribeiro, GGOS Silveira, ES Candido… - ACS Infectious …, 2020 - ACS Publications
The need for new antimicrobial therapies is evident, especially to reduce antimicrobial
resistance and minimize deleterious effects on gut microbiota. However, although diverse …
resistance and minimize deleterious effects on gut microbiota. However, although diverse …
Predictable modulation of cancer treatment outcomes by the gut microbiota
The gut microbiota has the potential to influence the efficacy of cancer therapy. Here, we
investigated the contribution of the intestinal microbiome on treatment outcomes in a …
investigated the contribution of the intestinal microbiome on treatment outcomes in a …
Probiotics Bifidobacterium lactis M8 and Lactobacillus rhamnosus M9 prevent high blood pressure via modulating the gut microbiota composition and host metabolic …
High-fructose intake is one of the high-risk factors for hypertension. Several probiotics have
been reported to reduce high blood pressure (BP) via modulating gut microbiota, but the …
been reported to reduce high blood pressure (BP) via modulating gut microbiota, but the …
[HTML][HTML] Emerging frontiers of antibiotics use and their impacts on the human gut microbiome
Antibiotics, the primary drugs used to cure bacterial diseases, are increasingly becoming
ineffective due to the emergence of multiple drug resistance (MDR) leading to recurrence of …
ineffective due to the emergence of multiple drug resistance (MDR) leading to recurrence of …