Aspergillus fumigatus and Aspergillosis in 2019
JP Latgé, G Chamilos - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …
[HTML][HTML] Fungal iron homeostasis with a focus on Aspergillus fumigatus
M Misslinger, P Hortschansky, AA Brakhage… - Biochimica et Biophysica …, 2021 - Elsevier
To maintain iron homeostasis, fungi have to balance iron acquisition, storage, and utilization
to ensure sufficient supply and to avoid toxic excess of this essential trace element. As …
to ensure sufficient supply and to avoid toxic excess of this essential trace element. As …
[HTML][HTML] Secretion of the siderophore rhizoferrin is regulated by the cAMP-PKA pathway and is involved in the virulence of Mucor lusitanicus
V Alejandre-Castañeda, JA Patiño-Medina… - Scientific Reports, 2022 - nature.com
Mucormycosis is a fungal infection caused by Mucorales, with a high mortality rate.
However, only a few virulence factors have been described in these organisms. This study …
However, only a few virulence factors have been described in these organisms. This study …
How do trade and economic growth impact environmental degradation? New evidence and policy implications from the ARDL approach
Due to various environmental degradation and natural resource depletion around the world,
researchers' and policymakers' attention has turned to what causes environmental …
researchers' and policymakers' attention has turned to what causes environmental …
At the metal–metabolite interface in Aspergillus fumigatus: towards untangling the intersecting roles of zinc and gliotoxin
AM Traynor, RA Owens, CM Coughlin… - …, 2021 - microbiologyresearch.org
Cryptic links between apparently unrelated metabolic systems represent potential new drug
targets in fungi. Evidence of such a link between zinc and gliotoxin (GT) biosynthesis in …
targets in fungi. Evidence of such a link between zinc and gliotoxin (GT) biosynthesis in …
Natural roles of nonribosomal peptide metabolites in fungi
S Oide, BG Turgeon - Mycoscience, 2020 - jstage.jst.go.jp
abstract Over 90 years have passed since Alexander Fleming's discovery of penicillin, the
first recognized, naturally occurring antibiotic. Penicillin is a representative of a group of …
first recognized, naturally occurring antibiotic. Penicillin is a representative of a group of …
Novel intermicrobial molecular interaction: Pseudomonas aeruginosa Quinolone Signal (PQS) modulates Aspergillus fumigatus response to iron
H Nazik, G Sass, SR Ansari, R Ertekin… - …, 2020 - microbiologyresearch.org
Pseudomonas aeruginosa (Pa) and Aspergillus fumigatus (Af), the commonest bacterium
and fungus in compromised host airways, compete for iron (Fe). The Pseudomonas …
and fungus in compromised host airways, compete for iron (Fe). The Pseudomonas …
[HTML][HTML] Anticipatory stress responses and immune evasion in fungal pathogens
A Pradhan, Q Ma, LJ de Assis, I Leaves… - Trends in …, 2021 - cell.com
In certain niches, microbes encounter environmental challenges that are temporally linked.
In such cases, microbial fitness is enhanced by the evolution of anticipatory responses …
In such cases, microbial fitness is enhanced by the evolution of anticipatory responses …
[HTML][HTML] Distinct transcriptional responses to fludioxonil in Aspergillus fumigatus and its ΔtcsC and Δskn7 mutants reveal a crucial role for Skn7 in the cell wall …
S Schruefer, A Pschibul, SSW Wong, T Sae-Ong… - BMC genomics, 2023 - Springer
Background Aspergillus fumigatus is a major fungal pathogen that causes severe problems
due to its increasing resistance to many therapeutic agents. Fludioxonil is a compound that …
due to its increasing resistance to many therapeutic agents. Fludioxonil is a compound that …
[HTML][HTML] Genome-Wide Association for Itraconazole Sensitivity in Non-resistant Clinical Isolates of Aspergillus fumigatus
S Zhao, W Ge, A Watanabe, JR Fortwendel… - Frontiers in fungal …, 2021 - frontiersin.org
Aspergillus fumigatus is a potentially lethal opportunistic pathogen that infects over~
200,000 people and causes~ 100,000 deaths per year globally. Treating A. fumigatus …
200,000 people and causes~ 100,000 deaths per year globally. Treating A. fumigatus …