Patient-reported functional impairment due to hearing loss and tinnitus after cisplatin-based chemotherapy

VA Sanchez, MM Shuey, PC Dinh Jr… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Cisplatin is widely used and highly ototoxic, but patient-reported functional
impairment because of cisplatin-related hearing loss (HL) and tinnitus has not been …

Impact of pain and adverse health outcomes on long-term US testicular cancer survivors

PC Dinh Jr, PO Monahan, SD Fosså… - JNCI: Journal of the …, 2024 - academic.oup.com
Background No study has quantified the impact of pain and other adverse health outcomes
on global physical and mental health in long-term US testicular cancer survivors or …

Balancing efficacy with long-term side-effects: can we safely de-escalate therapy for germ cell tumors?

J Shamash, K Ng - Expert Review of Anticancer Therapy, 2023 - Taylor & Francis
Introduction The success in the management of germ cell tumors has encouraged
researchers to pay more attention on long-term side effects and other survivorship issues …

Prevalence and risk factors for ototoxicity after cisplatin-based chemotherapy

VA Sanchez, PC Dinh Jr, J Rooker… - Journal of Cancer …, 2023 - Springer
Purpose Ototoxicity is a prominent side effect of cisplatin-based chemotherapy. There are
few reports, however, estimating its prevalence in well-defined cohorts and associated risk …

Omics sciences and precision medicine in testicular cancer

G Madeo, G Bonetti, PE Maltese, B Tanzi… - La Clinica …, 2023 - clinicaterapeutica.it
Cancer, a potentially fatal condition, is one of the leading causes of death worldwide. Among
males aged 20 to 35, the most common cancer in healthy individuals is testicular cancer …

Comprehensive Audiologic Analyses After Cisplatin-Based Chemotherapy

VA Sanchez, PC Dinh, PO Monahan, S Althouse… - JAMA …, 2024 - jamanetwork.com
Importance Cisplatin is highly ototoxic but widely used. Evidence is lacking regarding
cisplatin-related hearing loss (CRHL) in adult-onset cancer survivors with comprehensive …

Quercetin attenuates cisplatin-induced mitochondrial apoptosis via PI3K/Akt mediated inhibition of oxidative stress in pericytes and improves the blood labyrinth …

TL Huang, WJ Jiang, Z Zhou, TF Shi, M Yu, M Yu… - Chemico-Biological …, 2024 - Elsevier
Cisplatin (CDDP) is broadly employed to treat different cancers, whereas there are no drugs
approved by the Food and Drug Administration (FDA) for preventing its side effects …

[HTML][HTML] Milnacipran Has an Antihyperalgesic Effect on Cisplatin-Induced Neuropathy

SJ Cho, JY Lee, Y Jeong, SY Cho, DG Lee, JY Choi… - Pharmaceutics, 2023 - mdpi.com
(1) Background: Milnacipran is a typical serotonin–norepinephrine reuptake inhibitor and
has been shown to have analgesic effects in several pain models. However, its …

[HTML][HTML] Transcriptional Profile Changes after Noise-Induced Tinnitus in Rats

P Liu, X Xue, C Zhang, H Zhou, Z Ding, L Wang… - Brain Sciences, 2023 - mdpi.com
Tinnitus is an unpleasant symptom characterized by detective hearing without the actual
sound input. Despite numerous studies elucidating a variety of pathomechanisms inducing …

[HTML][HTML] Abnormal quantitative sudomotor axon reflex test results in patients with tinnitus as a possible indicator of small fiber neuropathy

HL Lee, HJ Lyou, JJ Song, CK Kim - Frontiers in Neurology, 2024 - frontiersin.org
A few cases of small fiber neuropathy (SFN) and tinnitus (TN) associated with coronavirus
disease 2019 have been reported. However, the relationship between SFN and TN has not …