Number of tumor foci predicts prognosis in papillary thyroid cancer

N Qu, L Zhang, Q Ji, Y Zhu, Z Wang, Q Shen, Y Wang… - BMC cancer, 2014 - Springer
Background Papillary thyroid cancer (PTC) often presents as multifocal. However, the
association of multifocality with poor prognosis remains controversial. The aim of this …

Immunohistochemical detection of p53 homolog p63 in solid cell nests, papillary thyroid carcinoma, and Hashimoto's thyroiditis: a stem cell hypothesis of papillary …

DE Burstein, C Nagi, BY Wang, P Unger - Human pathology, 2004 - Elsevier
Most models suggest that the cell of origin of papillary carcinoma is the mature thyroid
follicular epithelial cell. In a recent study, p63 was detected in papillary carcinoma …

Molecular evidence for the same clonal origin of multifocal papillary thyroid carcinomas

RP McCarthy, M Wang, TD Jones, RW Strate… - Clinical cancer …, 2006 - AACR
Purpose: Patients with papillary thyroid carcinoma often have two or more distinct papillary
tumors at thyroidectomy. Whether these multifocal papillary lesions are clonally related or …

[图书][B] Pediatric endocrinology: growth, adrenal, sexual, thyroid, calcium, and fluid balance disorders

F Lifshitz - 2006 - books.google.com
Celebrating more than twenty years as the single best source in the field, this Fifth Edition
has now expanded into two cornerstone volumes with 53 fully inclusive chapters and 73 …

Multifocality in well-differentiated thyroid carcinomas calls for total thyroidectomy

H Mazeh, Y Samet, D Hochstein, I Mizrahi, I Ariel… - The American Journal of …, 2011 - Elsevier
BACKGROUND: Multifocality is an important factor when recommending surgery for
papillary thyroid cancer (PTC). The aim of this study is to assess the incidence and …

Validation of ultrasound risk stratification systems for cervical lymph node metastasis in patients with thyroid cancer

JY Lee, RE Yoo, JH Rhim, KH Lee, KS Choi, I Hwang… - Cancers, 2022 - mdpi.com
Simple Summary Ultrasound (US) malignancy risk stratification systems (RSS) for cervical
lymph nodes (LNs) have not been fully established in patients with thyroid cancer. In this …

Clonality analysis of multifocal papillary thyroid carcinoma by using genetic profiles

Z Lu, J Sheng, Y Zhang, J Deng, Y Li… - The Journal of …, 2016 - Wiley Online Library
Papillary thyroid carcinoma (PTC) is the most common adult thyroid malignancy and often
presents with multiple anatomically distinct foci within the thyroid, known as multifocal …

Growth activity in hyperplastic and neoplastic human thyroid determined by an immunohistochemical staining procedure using monoclonal antibody MIB-1

R Katoh, CE Bray, K Suzuki, A Komiyama, A Hemmi… - Human pathology, 1995 - Elsevier
To increase our understanding of the basic biological mechanisms of thyroid diseases,
growth activity (GA) in 232 thyroid lesions was determined by immunohistochemistry using …

Different clonal origin of bilateral papillary thyroid carcinoma, with a review of the literature

E Kuhn, L Teller, S Piana, J Rosai, MJ Merino - Endocrine pathology, 2012 - Springer
Papillary thyroid carcinoma (PTC) often presents with two or more anatomically separate
foci. A long-standing argument is whether this multifocality is the result of multiple …

Clonal analysis of bilateral, recurrent, and metastatic papillary thyroid carcinomas

W Wang, H Wang, X Teng, H Wang, C Mao, R Teng… - Human pathology, 2010 - Elsevier
Papillary thyroid carcinoma usually presents as a multifocal disease; and tumors often recur
in the contralateral thyroid lobe, raising questions concerning their clonal origins. The …