[HTML][HTML] COVID-19 biomarkers at the crossroad between patient stratification and targeted therapy: the role of validated and proposed parameters

M Rizzi, D D'Onghia, S Tonello, R Minisini… - International Journal of …, 2023 - mdpi.com
Clinical knowledge about SARS-CoV-2 infection mechanisms and COVID-19
pathophysiology have enormously increased during the pandemic. Nevertheless, because …

[HTML][HTML] Importance of IP-10 as a biomarker of host immune response: Critical perspective as a target for biosensing

S Madhurantakam, ZJ Lee, A Naqvi… - Current Research in …, 2023 - Elsevier
While the exploration into biomolecules for diagnostic and prognostic devices continues to
develop, many molecules continue to be examined for individual diseases or treatments …

The glycosaminoglycan-binding chemokine fragment CXCL9 (74–103) reduces inflammation and tissue damage in mouse models of coronavirus infection

VLS Oliveira, CM Queiroz-Junior… - Frontiers in …, 2024 - frontiersin.org
Introduction Pulmonary diseases represent a significant burden to patients and the
healthcare system and are one of the leading causes of mortality worldwide. Particularly, the …

Cell‐Specific Regulation of Inflammatory Cytokines and Acute‐Phase Proteins by the Glucocorticoid Receptor

R Winkler, H Lu - Mediators of Inflammation, 2023 - Wiley Online Library
Background. Literature and data mining found abnormal induction of chemokine (C‐X‐C
motif) ligand 1 (CXCL1) and CXCL8 and down‐regulation of CXCL2 in inflammatory liver …

Large‐Scale Proteome Profiling Identifies Biomarkers Associated with Suspected Neurosyphilis Diagnosis

J Li, J Ma, MJ Liu, M Li, M Zhang, W Yin… - Advanced …, 2024 - Wiley Online Library
Neurosyphilis (NS) is a central nervous system (CNS) infection caused by Treponema
pallidum (T. pallidum). NS can occur at any stage of syphilis and manifests as a broad …

[HTML][HTML] YKL-40 promotes chemokine expression following drug-induced liver injury via TF-PAR1 pathway in mice

Z Jing-Lun, C Shuang, Z Li-Mei… - Frontiers in …, 2023 - frontiersin.org
Background: The inflammatory factor YKL-40 is associated with various inflammatory
diseases and is key to remodeling inflammatory cells and tissues. YKL-40 (Chi3l1) promotes …

[HTML][HTML] Neonatal Chlamydia muridarum respiratory infection causes neuroinflammation within the brainstem during the early postnatal period

KE Hedley, HM Gomez, E Kecelioglu… - Journal of …, 2024 - Springer
Respiratory infections are one of the most common causes of illness and morbidity in
neonates worldwide. In the acute phase infections are known to cause wide-spread …

[HTML][HTML] Understanding yellow fever-associated myocardial injury: an autopsy study

FR Giugni, VD Aiello, CS Faria, SZ Pour… - Ebiomedicine, 2023 - thelancet.com
Background Yellow fever (YF) is a viral hemorrhagic fever, endemic in parts of South
America and Africa. There is scarce evidence about the pathogenesis of the myocardial …

[HTML][HTML] Identification of interferon-stimulated genes with modulated expression during hepatitis E virus infection in pig liver tissues and human HepaRG cells

L Meyer, I Duquénois, S Gellenoncourt… - Frontiers in …, 2023 - frontiersin.org
Introduction Hepatitis E virus (HEV) is a common cause of enterically transmitted acute
hepatitis worldwide. The virus is transmitted by the fecal-oral route via the consumption of …

TLR4/7‐mediated host‐defense responses of gingival epithelial cells

N Chiba, R Tada, T Ohnishi… - Journal of Cellular …, 2024 - Wiley Online Library
Gingival epithelial cells (GECs) are physical and immunological barriers against outward
pathogens while coping with a plethora of non‐pathogenic commensal bacteria. GECs …