[HTML][HTML] Immunotherapy in hematologic malignancies: achievements, challenges and future prospects

L Tang, Z Huang, H Mei, Y Hu - Signal Transduction and Targeted …, 2023 - nature.com
The immune-cell origin of hematologic malignancies provides a unique avenue for the
understanding of both the mechanisms of immune responsiveness and immune escape …

[HTML][HTML] Endothelial dysfunction syndromes after allogeneic stem cell transplantation

D Vythoulkas, P Tsirigotis, M Griniezaki, I Konstantellos… - Cancers, 2023 - mdpi.com
Simple Summary Hemato-poietic stem cell transplantation is associated with significant
endothelial dysfunction, which may result in severe complications. Endothelial dysfunction …

Defibrotide plus best standard of care compared with best standard of care alone for the prevention of sinusoidal obstruction syndrome (HARMONY): a randomised …

SA Grupp, S Corbacioglu, HJ Kang… - The Lancet …, 2023 - thelancet.com
Background Sinusoidal obstruction syndrome, also known as veno-occlusive disease, is a
potentially life-threatening complication of haematopoietic stem-cell transplantation (HSCT) …

[HTML][HTML] The role of complement in HSCT-TMA: basic science to clinical practice

S Meri, D Bunjes, R Cofiell, S Jodele - Advances in Therapy, 2022 - Springer
Hematopoietic stem cell transplantation-associated thrombotic microangiopathy (HSCT-
TMA) is a common complication occurring post-HSCT and is associated with substantial …

Clinical utilization of blinatumomab and inotuzumab immunotherapy in children with relapsed or refractory B‐acute lymphoblastic leukemia

CF Contreras, CS Higham, A Behnert… - Pediatric blood & …, 2021 - Wiley Online Library
Background The treatment paradigm for patients with relapsed/refractory B‐cell acute
lymphoblastic leukemia (rrALL) has been revolutionized given recent clinical trials …

How I treat transplant-eligible patients with myelofibrosis

N Kröger, C Wolschke, N Gagelmann - Blood, 2023 - ashpublications.org
Despite the approval of Janus kinase inhibitors and novel agents for patients with
myelofibrosis (MF), disease-modifying responses remain limited, and hematopoietic stem …

[HTML][HTML] Current incidence, severity, and management of veno-occlusive disease/sinusoidal obstruction syndrome in adult allogeneic HSCT recipients: an EBMT …

T Ruutu, C Peczynski, M Houhou, E Polge… - Bone Marrow …, 2023 - nature.com
The current incidence, diagnostic policy, management, and outcome of VOD/SOS at EBMT
centers were studied. All centers that had performed allogeneic HSCTs in adult patients …

[HTML][HTML] Inotuzumab ozogamicin in B-cell precursor acute lymphoblastic leukemia: efficacy, toxicity, and practical considerations

JD Rubinstein, MM O'Brien - Frontiers in Immunology, 2023 - frontiersin.org
Inotuzumab ozogamicin (InO) is an antibody drug conjugate composed of a humanized
monoclonal antibody targeting the cell surface receptor CD22 coupled to a cytotoxic …

[HTML][HTML] Incidence and risk factors for acute kidney injury after allogeneic stem cell transplantation: a prospective study

A Andronesi, B Sorohan, A Burcea, L Lipan… - Biomedicines, 2022 - mdpi.com
(1) Background: Acute kidney injury (AKI) is a serious complication of hematopoietic stem
cell transplantation (HSCT).(2) Methods: The aim was to identify the incidence, severity, and …

[HTML][HTML] Hepatic venous pressure gradient in sinusoidal obstruction syndrome: diagnostic value and link with histological lesions

SB Gressens, D Cazals-Hatem, V Lloyd, A Plessier… - JHEP Reports, 2022 - Elsevier
Background & Aims Liver sinusoidal obstruction syndrome (SOS) is a well-established
complication of myeloablative conditioning regimens used in hematopoietic stem cell …