Biomaterial‐mediated inflammation and fibrosis remain a prominent challenge in designing
materials to support tissue repair and regeneration. Despite the many biomaterial …

All biomaterials, when implanted in vivo, elicit cellular and tissue responses. These
responses include the inflammatory and wound healing responses, foreign body reactions …

COVID-19 is a disease with unique characteristics that include lung thrombosis, frequent
diarrhoea, abnormal activation of the inflammatory response and rapid deterioration of lung …

The healing process after implantation of biomaterials involves the interaction of many
contributing factors. Besides their in vivo functionality, biomaterials also require …

Body implants and implantable medical devices have dramatically improved and prolonged
the life of countless patients. However, our body repair mechanisms have evolved to isolate …

Diversity and plasticity are hallmarks of cells of the monocyte-macrophage lineage. In
response to IFNs, Toll-like receptor engagement, or IL-4/IL-13 signaling, macrophages …

The concept of an alternative pathway of macrophage activation has stimulated interest in its
definition, mechanism, and functional significance in homeostasis and disease. We assess …

A key for long-term survival and function of biomaterials is that they do not elicit a detrimental
immune response. As biomaterials can have profound impacts on the host immune …

The macrophage, a versatile cell type prominently involved in host defense and immunity,
assumes a distinct state of alternative activation in the context of polarized type 2 immune …

In all animal cells, phospholipids are asymmetrically distributed between the outer and inner
leaflets of the plasma membrane. This asymmetrical phospholipid distribution is disrupted in …