Methamphetamine: effects on the brain, gut and immune system
MD Prakash, K Tangalakis, J Antonipillai… - Pharmacological …, 2017 - Elsevier
Methamphetamine (METH) is a powerful central nervous system stimulant which elevates
mood, alertness, energy levels and concentration in the short-term. However, chronic use …
mood, alertness, energy levels and concentration in the short-term. However, chronic use …
Methamphetamine dysregulation of the central nervous system and peripheral immunity
DR Miller, M Bu, A Gopinath, LR Martinez… - … of Pharmacology and …, 2021 - ASPET
Methamphetamine (METH) is a potent psychostimulant that increases extracellular
monoamines, such as dopamine and norepinephrine, and affects multiple tissue and cell …
monoamines, such as dopamine and norepinephrine, and affects multiple tissue and cell …
Methamphetamine induces systemic inflammation and anxiety: the role of the gut–immune–brain axis
M Davidson, M Mayer, A Habib, N Rashidi… - International journal of …, 2022 - mdpi.com
Methamphetamine (METH) is a highly addictive drug abused by millions of users worldwide,
thus becoming a global health concern with limited management options. The inefficiency of …
thus becoming a global health concern with limited management options. The inefficiency of …
Escalating dose-multiple binge methamphetamine treatment elicits neurotoxicity, altering gut microbiota and fecal metabolites in mice
LJ Chen, X Zhi, KK Zhang, LB Wang, JH Li… - Food and Chemical …, 2021 - Elsevier
Methamphetamine (METH) is an addictive and illegal psychostimulant drug that can cause
multiple organ dysfunction, especially in the central nervous system (CNS). Gut microbiota …
multiple organ dysfunction, especially in the central nervous system (CNS). Gut microbiota …
Methamphetamine (MA) use and MA-induced psychosis are associated with increasing aberrations in the compensatory immunoregulatory system, interleukin-1α …
R Kalayasiri, K Dadwat, S Thika… - Translational …, 2023 - nature.com
There are only a few studies reporting on the immunological profiles of methamphetamine
(MA) use, MA dependency, or MA-induced psychosis (MAP). This study measured M1 …
(MA) use, MA dependency, or MA-induced psychosis (MAP). This study measured M1 …
Drugs and bugs: the gut-brain axis and substance use disorders
S Simpson, R Mclellan, E Wellmeyer, F Matalon… - Journal of Neuroimmune …, 2022 - Springer
Substance use disorders (SUDs) represent a significant public health crisis. Worldwide,
5.4% of the global disease burden is attributed to SUDs and alcohol use, and many more …
5.4% of the global disease burden is attributed to SUDs and alcohol use, and many more …
Current understanding of methamphetamine-associated dopaminergic neurodegeneration and psychotoxic behaviors
EJ Shin, DK Dang, TV Tran, HQ Tran, JH Jeong… - Archives of Pharmacal …, 2017 - Springer
Clinical and preclinical studies have indicated that chronic methamphetamine (MA) use is
associated with extensive neurodegeneration, psychosis, and cognitive impairment …
associated with extensive neurodegeneration, psychosis, and cognitive impairment …
High prevalence of co-occurring substance use in individuals with opioid use disorder
Objective Funding to address the current opioid epidemic has focused on treatment of opioid
use disorder (OUD); however, rates of other substance use disorders (SUDs) remain high …
use disorder (OUD); however, rates of other substance use disorders (SUDs) remain high …
The sigma-1 receptor as a regulator of dopamine neurotransmission: a potential therapeutic target for methamphetamine addiction
DO Sambo, JJ Lebowitz, H Khoshbouei - Pharmacology & therapeutics, 2018 - Elsevier
Methamphetamine (METH) abuse is a major public health issue around the world, yet there
are currently no effective pharmacotherapies for the treatment of METH addiction. METH is a …
are currently no effective pharmacotherapies for the treatment of METH addiction. METH is a …
Alterations to the gastrointestinal microbiome associated with methamphetamine use among young men who have sex with men
Methamphetamine (MA) use is a major public health problem in the United States,
especially among people living with HIV (PLWH). Many MA-induced neurotoxic effects are …
especially among people living with HIV (PLWH). Many MA-induced neurotoxic effects are …