Neutrophils in Cancer immunotherapy: friends or foes?

X Huang, E Nepovimova, V Adam, L Sivak, Z Heger… - Molecular Cancer, 2024 - Springer
Neutrophils play a Janus-faced role in the complex landscape of cancer pathogenesis and
immunotherapy. As immune defense cells, neutrophils release toxic substances, including …

[HTML][HTML] The response of two polar monocyte subsets to inflammation

P Vishnyakova, A Poltavets, E Karpulevich… - Biomedicine & …, 2021 - Elsevier
Macrophages are a central component of innate immunity that play an important role in the
defense of the organism. Macrophages are highly plastic and are activated by interaction …

Monocyte subset distribution and surface expression of HLA-DR and CD14 in patients after cardiopulmonary resuscitation

A Asmussen, HJ Busch, T Helbing, X Bemtgen… - Scientific Reports, 2021 - nature.com
Systemic inflammation is a major feature of the post-cardiac arrest syndrome. The three
monocyte subpopulations are thought to play an important role in this inflammatory state …

[HTML][HTML] High-intensity interval training reduces monocyte activation in obese adults

MA de Matos, BCC Garcia, DV Vieira… - Brain, behavior, and …, 2019 - Elsevier
Alterations in the distribution and activation of monocyte subsets are frequently observed in
individuals with obesity and their participation in the pathological complications of obesity is …

Expression of DNAM-1 (CD226) on inflammatory monocytes

A Van Vo, E Takenaka, A Shibuya, K Shibuya - Molecular immunology, 2016 - Elsevier
DNAM-1 is an activating receptor expressed on NK cells and T cells and plays an important
role in cytotoxicity of these cells against target cells. Although the role of DNAM-1 in the …

Metabolic syndrome mediates proinflammatory responses of inflammatory cells in preeclampsia

G Jabalie, M Ahmadi, L Koushaeian… - American journal of …, 2019 - Wiley Online Library
Problem To investigate whether metabolic syndrome (MetS) is associated with exacerbation
of inflammatory responses in preeclamptic (PE) patients, the dynamic changes of Th17 and …

Clinical relevance and cellular source of elevated soluble urokinase plasminogen activator receptor (su PAR) in acute liver failure

A Koch, HW Zimmermann, N Gassler… - Liver …, 2014 - Wiley Online Library
Abstract Background & Aims Acute liver failure (ALF) is a life‐threatening condition with a
high mortality rate. The expression of urokinase plasminogen activator receptor (uPAR …

HMGB1+ microparticles present in urine are hallmarks of nephritis in patients with systemic lupus erythematosus

C Burbano, JA Gómez‐Puerta… - European journal of …, 2019 - Wiley Online Library
Non‐classical monocytes infiltrate the kidney parenchyma and participate in tissue damage
in patients with lupus nephritis (LN). Circulating microparticles (MPs) seem to play critical …

The COX-inhibitor indomethacin reduces Th1 effector and T regulatory cells in vitro in Mycobacterium tuberculosis infection

K Tonby, I Wergeland, NV Lieske, D Kvale… - BMC infectious …, 2016 - Springer
Background Tuberculosis (TB) causes a major burden on global health with long and
cumbersome TB treatment regimens. Host-directed immune modulating therapies have …

Monocyte, macrophage, and dendritic cell development: the human perspective

M Collin, V Bigley - Myeloid Cells in Health and Disease: A …, 2017 - Wiley Online Library
Monocytes, macrophages, and dendritic cells (DCs) are populations of myeloid
mononuclear cells (MMCs) that provide critical sensing functions in innate immunity and a …