The functions, purposes, and roles of metallothioneins have been the subject of
speculations since the discovery of the protein over 60 years ago. This article guides …

The human body cannot store zinc reserves, so a deficiency can arise relatively quickly, eg,
through an improper diet. Severe zinc deficiency is rare, but mild deficiencies are common …

Alzheimer's disease (AD) 1− 3 is the most common form of dementia (estimated∼ 50− 60%
of all cases), associated with loss of memory (in particular episodic memory), cognitive …

Iron (Fe), copper (Cu), and zinc (Zn) are microelements essential for the proper functioning
of living organisms. These elements participatein many processes, including cellular …

The discovery of the cadmium (Cd)-binding protein from horse kidney in 1957 marked the
birth of research on this low-molecular weight, cysteine-rich protein called metallothionein …

Metallothioneins (MTs) are a family of metal-binding proteins virtually expressed in all
organisms including prokaryotes, lower eukaryotes, invertebrates and mammals. These …

Metallothioneins are cysteine-rich, small metal-binding proteins present in various
mammalian tissues. Of the four common metallothioneins, MT-1 and MT-2 (MTs) are …

Metallothioneins (MTs) are a class of ubiquitously occurring low molecular mass, cysteine-
and metal-rich proteins containing sulfur-based metal clusters formed with Zn (II), Cd (II), and …

MTs are small cysteine-rich proteins that chelate metal ions such as Cu+ and Zn2+, and are
widely distributed in several life domains, in particular the eukaryotic one. They are present …

Cadmium is known for its toxicity in animals and man as it is not used in these species. Its
only role in biology is as a zinc replacement at the catalytic site of a particular class of …