Patients admitted to the intensive care unit (ICU) are in need of continuous organ
replacement strategies and specialized care, for example because of neurological …

Objective Sleep disturbance and delirium are common problems experienced by critically ill
patients in the intensive care unit (ICU). These interrelated issues increase the length of stay …

OBJECTIVES: To evaluate the sleep and circadian rest-activity pattern of critical COVID-19
survivors 3 months after hospital discharge. DESIGN: Observational, prospective study …

Rationale Vital signs follow circadian patterns in both healthy volunteers and critically ill
patients, which seem to be influenced by disease severity in the latter. In this study we …

Aligning timing of nutritional intake, physical activity, and/or medication with circadian
rhythms are potential strategies to reset peripheral circadian rhythms and may enhance ICU …

The objective of this study was to understand the existing practices and attitudes regarding
inpatient sleep at the 2020 US News and World Report (USNWR) Honor Roll pediatric (n …

Intensive care units (ICUs) provide advanced clinical care to support critically ill patients.
Inherently, the ICU environment subjects patients to an inordinate amount of clinical …

BACKGROUND: We aimed to further validate our previously published animal model for
delirium by testing the hypothesis that in aged mice, Anesthesia, Surgery and simulated ICU …

Background and objective NSAIDs inhibit cyclooxygenase, but their role in aging and other
diseases is not well understood. Our group previously showed the potential benefit of …

Sleep is a complex process influenced by biological and environmental factors.
Disturbances of sleep quantity and quality occur frequently in the critically ill and remain …