Malaria still has a devastating impact on public health and welfare in Cameroon. Despite the
increasing number of studies conducted on disease prevalence, transmission patterns or …

Antimicrobial treatment failure threatens our ability to control infections. In addition to
antimicrobial resistance, treatment failures are increasingly understood to derive from cells …

Background Plasmodium vivax exacts a significant toll on health worldwide, yet few efforts to
date have quantified the extent and temporal trends of its global distribution. Given the …

The technical genesis and practice of 8-aminoquinoline therapy of latent malaria offer
singular scientific, clinical, and public health insights. The 8-aminoquinolines brought …

Importance Latent hepaticPlasmodium vivaxhypnozoites provoke repeated clinical attacks
called relapses. Only primaquine phosphate kills hypnozoites, and its therapeutic activity …

Background In most of the Americas, the recommended treatment to prevent relapse of
Plasmodium vivax malaria is primaquine at a total dose of 3.5 mg per kilogram of body …

Emerging antimalarial drug resistance may undermine current efforts to control and
eliminate Plasmodium vivax, the most geographically widespread yet neglected human …

The global burden of Plasmodium vivax malaria is obscure and insidious | PLOS Medicine Skip
to main content Advertisement PLOS Medicine Browse Current Issue Journal Archive Special …

Background Despite recent intensification of control measures, Plasmodium vivax poses a
major challenge for malaria elimination efforts. Liver-stage hypnozoite parasites that cause …

Background The 8-aminoquinoline antimalarials, the only drugs which prevent relapse of
vivax and ovale malaria (radical cure), cause dose-dependent oxidant haemolysis in …