Background Psychedelic therapy shows promise for Major Depressive Disorder, especially
when treatment-resistant, as well as life-threatening illness distress. The objective of this …

Psychedelics, also known as classical hallucinogens, have been investigated for decades
due to their potential therapeutic effects in the treatment of neuropsychiatric and substance …

Importance Psilocybin shows promise as a treatment for major depressive disorder (MDD).
Objective To evaluate the magnitude, timing, and durability of antidepressant effects and …

Background Psilocybin has been suggested as a novel, rapid-acting treatment for
depression. Two consecutive doses have been shown to markedly decrease symptom …

Design Open-label Randomized Randomized, double-blind, placebo-controlled
Randomized, double-blind, placebo-controlled Randomized, double-blind, placebo …

Background: Several early phase studies have demonstrated that psilocybin-assisted
therapy has rapid-acting and persisting antidepressant effects from just one or two doses …

Research in the last decade has expressed considerable optimism about the clinical
potential of psychedelics for the treatment of mental disorders. This optimism is reflected in …

Psilocybin is a psychedelic with therapeutic potential. While there is growing evidence that
psilocybin exerts its beneficial effects through enhancing neural plasticity, the exact brain …

The aim of this review was to determine the effect of psilocybin on depressive symptoms in
patients diagnosed with life-threatening illnesses or major depressive disorder. Systematic …

Lysergic acid diethylamide (LSD) and similar psychoactive drugs have been used in
psychotherapy since 1949, when the first clinical study with lower-dose LSD showed …