The roles of adipose tissue macrophages in human disease

W Liang, Y Qi, H Yi, C Mao, Q Meng, H Wang… - Frontiers in …, 2022 - frontiersin.org
Macrophages are a population of immune cells functioning in antigen presentation and
inflammatory response. Research has demonstrated that macrophages belong to a cell …

[HTML][HTML] Multifunctional nanoprobes for macrophage imaging

H Deng, L Xu, J Ju, X Mo, G Ge, X Zhu - Biomaterials, 2022 - Elsevier
Imaging and tracking macrophage behaviors in vivo are essential to reveal its biological
function and fate in various diseases. Small molecular probes suffer from poor macrophage …

[HTML][HTML] Environmental endocrine disruptor Bisphenol A induces metabolic derailment and obesity via upregulating IL-17A in adipocytes

X Hong, Y Zhou, Z Zhu, Y Li, Z Li, Y Zhang, X Hu… - Environment …, 2023 - Elsevier
Abstract Background Bisphenol A (BPA), a ubiquitous environmental endocrine disruptor,
has been extensively demonstrated to be associated with metabolic disorders, including …

cGAS/STING and innate brain inflammation following acute high-fat feeding

SE Elzinga, R Henn, BJ Murdock, B Kim… - Frontiers in …, 2022 - frontiersin.org
Obesity, prediabetes, and diabetes are growing in prevalence worldwide. These metabolic
disorders are associated with neurodegenerative diseases, particularly Alzheimer's disease …

Adipose tissue as a therapeutic target for vascular damage in Alzheimer's disease

M Bettinetti‐Luque, L Trujillo‐Estrada… - British Journal of …, 2024 - Wiley Online Library
Adipose tissue has recently been recognized as an important endocrine organ that plays a
crucial role in energy metabolism and in the immune response in many metabolic tissues …

Structural characterization and macrophage polarization-modulating activity of a novel polysaccharide from large yellow tea

H Wang, S Xu, D Li, Z Xie - Journal of Agricultural and Food …, 2022 - ACS Publications
A novel homogeneous polysaccharide (LYP-S3) that promotes the M2 polarization of
macrophages was obtained from large yellow tea by a bioactivity-guided sequential …

Large yellow tea polysaccharides ameliorate obesity-associated metabolic syndrome by promoting M2 polarization of adipose tissue macrophages

H Wang, L Wang, H Cheng, H Ge, Z Xie, D Li - Food & Function, 2023 - pubs.rsc.org
Obesity-induced metabolic syndrome is strongly associated with infiltrated adipose tissue
macrophages (ATMs). Large yellow tea, a traditional functional beverage in China, has been …

Emodin inhibits lipid accumulation and inflammation in adipose tissue of high‐fat diet‐fed mice by inducing M2 polarization of adipose tissue macrophages

F Yu, N Yu, J Peng, Y Zhao, L Zhang… - The FASEB …, 2021 - Wiley Online Library
Adipose tissue macrophages (ATMs) represent the most abundant leukocytes in adipose
tissue (AT). An increase in number and a phenotypical switch of ATMs during the …

Obesity, inflammation, and heart failure: links and misconceptions

F Triposkiadis, A Xanthopoulos, RC Starling… - Heart Failure …, 2022 - Springer
Obesity has been linked with heart failure (HF) with preserved left ventricular (LV) ejection
fraction (HFpEF). This link has been attributed to obesity-induced metabolic and …

[HTML][HTML] Blocking Fas-signaling in adipocytes and hepatocytes prevents obesity-associated inflammation, insulin resistance, and hepatosteatosis

S Bae, I Ullah, J Beloor, J Lim, K Chung, Y Yi… - Journal of Industrial and …, 2024 - Elsevier
Fas-mediated apoptosis in the adipose tissue and the liver plays a pivotal role in the onset of
obesity-associated inflammation, insulin resistance, hepatic steatosis, and metabolic …