[HTML][HTML] Protective Effects of (E)-β-Caryophyllene (BCP) in Chronic Inflammation

R Scandiffio, F Geddo, E Cottone, G Querio… - Nutrients, 2020 - mdpi.com
(E)-β-caryophyllene (BCP) is a bicyclic sesquiterpene widely distributed in the plant
kingdom, where it contributes a unique aroma to essential oils and has a pivotal role in the …

Analgesic potential of terpenes derived from Cannabis sativa

E Liktor-Busa, A Keresztes, J LaVigne… - Pharmacological …, 2021 - ASPET
Pain prevalence among adults in the United States has increased 25% over the past two
decades, resulting in high health-care costs and impacts to patient quality of life. In the last …

[HTML][HTML] Advances and perspectives in tissue culture and genetic engineering of cannabis

M Hesami, A Baiton, M Alizadeh, M Pepe… - International journal of …, 2021 - mdpi.com
For a long time, Cannabis sativa has been used for therapeutic and industrial purposes. Due
to its increasing demand in medicine, recreation, and industry, there is a dire need to apply …

A mechanistic review on immunomodulatory effects of selective type two cannabinoid receptor β‐caryophyllene

V Baradaran Rahimi, VR Askari - Biofactors, 2022 - Wiley Online Library
Abstract β‐Caryophyllene (BCP) is a plant‐derived compound and occurs naturally in
various foods and spices, including cinnamon, citrus, fruits, clove, curry, and pepper. BCP …

[HTML][HTML] A focused review on CB2 receptor-selective pharmacological properties and therapeutic potential of β-caryophyllene, a dietary cannabinoid

HM Hashiesh, C Sharma, SN Goyal, B Sadek… - Biomedicine & …, 2021 - Elsevier
The endocannabinoid system (ECS), a conserved physiological system emerged as a novel
pharmacological target for its significant role and potential therapeutic benefits ranging from …

[HTML][HTML] β-Caryophyllene, a natural dietary CB2 receptor selective cannabinoid can be a candidate to target the trinity of infection, immunity, and inflammation in Covid …

NK Jha, C Sharma, HM Hashiesh… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease (COVID-19), caused by novel severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is an ongoing pandemic and presents a public health …

[HTML][HTML] Cannabinoids in traumatic brain injury and related neuropathologies: preclinical and clinical research on endogenous, plant-derived, and synthetic …

BR Lins, CC Anyaegbu, SC Hellewell, M Papini… - Journal of …, 2023 - Springer
Traumatic brain injury is common, and often results in debilitating consequences. Even mild
traumatic brain injury leaves approximately 20% of patients with symptoms that persist for …

[HTML][HTML] Combined non-psychoactive Cannabis components cannabidiol and β-caryophyllene reduce chronic pain via CB1 interaction in a rat spinal cord injury model

A Eeswara, A Pacheco-Spiewak, S Jergova, J Sagen - PloS one, 2023 - journals.plos.org
The most frequently reported use of medical marijuana is for pain relief. However, its
psychoactive component Δ9-tetrahydrocannabinol (THC) causes significant side effects …

[HTML][HTML] Multi-target effects of ß-caryophyllene and carnosic acid at the crossroads of mitochondrial dysfunction and neurodegeneration: from oxidative stress to …

R Iorio, G Celenza, S Petricca - Antioxidants, 2022 - mdpi.com
Inflammation and oxidative stress are interlinked and interdependent processes involved in
many chronic diseases, including neurodegeneration, diabetes, cardiovascular diseases …

Evaluation of the terpenes β-caryophyllene, α-terpineol, and γ-terpinene in the mouse chronic constriction injury model of neuropathic pain: Possible cannabinoid …

JA Bilbrey, YT Ortiz, JS Felix, LR McMahon… - …, 2022 - Springer
Pain is one of the most common reasons to seek medical attention, and chronic pain is a
worldwide epidemic. Anecdotal reports suggest cannabis may be an effective analgesic. As …