Natural sesquiterpenoids caryophyllene and caryophyllene oxide are important resources
for organic and medicinal chemistry. Due to their peculiar structure, these sesquiterpenoids …

Chronic pain and its associated comorbidities are difficult to treat, even when the most
potent analgesic compounds are used. Thus, research on new strategies to effectively …

The most frequently reported use of medical marijuana is for pain relief. However, its
psychoactive component Δ9-tetrahydrocannabinol (THC) causes significant side effects …

Hemp seed flour represents a potential ingredient for protein enrichment of gluten-free
bakery products, the nutritional value of which could be further increased by fermentation …

Neurological disorders related to neuroinfections are highly prevalent in Sub-Saharan Africa
(SSA), constituting a major cause of disability and economic burden for patients and society …

Cocaine abuse continues to be a serious health problem worldwide. Despite intense
research, there is still no FDA-approved medication to treat cocaine use disorder (CUD). In …

In light of the current International Association for the Study of Pain (IASP) clinical practice
guidelines (CPGs) and the European Society for Medical Oncology (ESMO) guidelines, the …

Neuropathic pain remains prevalent and challenging to manage and is often comorbid with
depression and anxiety. The new approach that simultaneously targets neuropathic pain …

The increasing legalization of Cannabis sativa plant products has sparked growing interest
in their therapeutic applications. Prohibition laws established in 1937 hindered formal …

Cannabinoids help in pain treatment through their action on CB1 and CB2 receptors. β-
caryophyllene (BCP), an ancient remedy to treat pain, is a sesquiterpene found in large …