The Endocannabinoid System (ECS) is a well-studied system that influences a variety of
physiological activities. It is evident that the ECS plays a significant role in metabolic …

Although rare, amoebic keratitis (AK) is a disease caused by Acanthamoeba spp. that can
lead to blindness. The drugs currently available for its treatment are very toxic, which has …

Nucleoside reverse transcriptase inhibitors (NRTIs), drugs used to treat HIV infection, can
cause neuropathic pain (NP) and neuroinflammation. An NRTI, 2′-3′-dideoxycytidine …

The compounds present in hemp show multidirectional biological activity. It is related to the
presence of secondary metabolites, mainly cannabinoids, terpenes, and flavonoids, and the …

The current drug therapy for schizophrenia effectively treats acute psychosis and its
recurrence; however, this mental disorder's cognitive and negative symptoms are still poorly …

Sesquiterpenes are terpene compounds, containing three isoprene units rearranged in a
wide variety of structures. They occur widely in nature, not only in plants but also in fungi and …

Background: Cannabis sativa L. is an annual plant from the Cannabaceae family. In
Morocco, it has a long-standing traditional use. This study aimed to perform a chemical …

The use of paclitaxel as a chemotherapeutic drug is limited by the development of dose-
dependent paclitaxel-induced neuropathic pain (PINP). Recently, we observed that the …

Mental disorders account for one of the most prevalent categories of the burden of disease
worldwide, with depression expected to be the largest contributor by 2030, closely followed …

The endocannabinoid system is a complex lipid signaling network that has evolved to be a
key regulator of pro-homeostatic pathways for the organism. Its involvement in numerous …