Immune checkpoint inhibitors and neurotoxicity: a focus on diagnosis and management for a multidisciplinary approach

D Speranza, M Santarpia, F Luppino… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Despite immune checkpoint inhibitors (ICIs) have revolutionized cancer
treatment, the consequential over activation of the immune system is often complicated by …

[HTML][HTML] Immune-Related Adverse Events Due to Cancer Immunotherapy: Immune Mechanisms and Clinical Manifestations

S Casagrande, GB Sopetto, G Bertalot, R Bortolotti… - Cancers, 2024 - mdpi.com
Simple Summary This review comprehensively summarizes the pathogenic mechanisms
responsible for immune-related Adverse Events (irAEs) arising from self-tolerance loss due …

Acute kidney injury in patients treated with immune checkpoint inhibitors: a single-center retrospective study

P Zhou, B Liu, N Shen, X Fan, S Lu, Z Kong, Y Gao… - Renal …, 2024 - Taylor & Francis
Background Immune checkpoint inhibitor-associated acute kidney injury (ICI-AKI) is the most
common renal complication and has attracted increasing amounts of attention. However …

[HTML][HTML] OCLN as a novel biomarker for prognosis and immune infiltrates in kidney renal clear cell carcinoma: an integrative computational and experimental …

Z Jia, Y Kong, C Wang, Z Fu, Z Tian, Y Sun… - Frontiers in …, 2023 - frontiersin.org
Background Occludin (OCLN) is an important tight junction protein and has been reported to
be abnormally expressed in the development of malignant tumors. However, its biomarker …

[HTML][HTML] Immunotherapy of Clear-Cell Renal-Cell Carcinoma

S Grigolo, L Filgueira - Cancers, 2024 - mdpi.com
Simple Summary Immunotherapeutic synergy represents the cornerstone of the treatment
intended for patients with clear-cell renal-cell carcinoma. In most cases, this type of cancer …

The Nephrotoxicity of Checkpoint Inhibitors: A Mini Review

F Mahmoodpoor, M Ardalan, A Nasibova… - International Journal of …, 2024 - ijdrug.com
Immune checkpoint inhibitors (ICIs) have established promising therapeutic outcomes in the
treatment of more than 17 tumors and are being used more frequently. Although these drugs …

INHIBITORI KONTROLNIH TOČAKA I BUBREG.

M GNJIDIĆ - Lijecnicki Vjesnik, 2023 - search.ebscohost.com
Inhibitori kontrolnih točaka (engl. ICIs) su humanizirana monoklonska protutijela koja vežući
se na receptore na imunosnim stanicama, otpuštaju kočnicu imunološke tolerancije na …