[HTML][HTML] Curcumin: An epigenetic regulator and its application in cancer

T Ming, Q Tao, S Tang, H Zhao, H Yang, M Liu… - Biomedicine & …, 2022 - Elsevier
Nowadays, one of the leading causes of death in humans is cancer, which is still on the rise
globally and is in great need of intense study on the pathogenic mechanism and effective …

Herbal approach for treatment of cancer using curcumin as an anticancer agent: A review on novel drug delivery systems

U Hani, BHJ Gowda, A Siddiqua, S Wahab… - Journal of Molecular …, 2023 - Elsevier
The polyphenol compound curcumin originates from the rhizomes of Curcuma longa Linn.
The anti-cancer effects of curcumin and its analogues are described in extensive detail and …

Curcumin induces apoptosis of chemoresistant lung cancer cells via ROS-regulated p38 MAPK phosphorylation

MF Wu, YH Huang, LY Chiu, SH Cherng… - International journal of …, 2022 - mdpi.com
This study aimed to challenge chemoresistance by curcumin (CUR) with drug-selected
human lung cancer A549 sublines that continuously proliferate in the present of docetaxel …

Polymeric nanomicelles of curcumin: Potential applications in cancer

L Farhoudi, P Kesharwani, M Majeed… - International Journal of …, 2022 - Elsevier
Natural compounds, primarily derived from plants, have been isolated and evaluated as
alternative and complementary treatments for cancer. Curcumin has been proven to be …

Curcumin and plumbagin synergistically target the PI3K/Akt/mTOR pathway: a prospective role in cancer treatment

I Ahmad, M Hoque, SSM Alam, TA Zughaibi… - International journal of …, 2023 - mdpi.com
Cancer development is associated with the deregulation of various cell signaling pathways
brought on by certain genetic and epigenetic alterations. Therefore, novel therapeutic …

Recent advances in codelivery of curcumin and siRNA as anticancer therapeutics

M Sanati, AR Afshari, P Kesharwani… - European Polymer …, 2023 - Elsevier
Addressing the need for effective cancer chemotherapy with low adverse effects has been
partially possible through innovative therapeutic approaches combining chemotherapeutics …

Identification of key genes in colorectal cancer diagnosis by weighted gene co-expression network analysis

M Mortezapour, L Tapak, F Bahreini, R Najafi… - Computers in Biology …, 2023 - Elsevier
Background The purpose of this study was using bioinformatics tools to identify biomarkers
and molecular factors involved in the diagnosis of colorectal cancer, which are effective for …

Cancer metabolism as a therapeutic target and review of interventions

MTJ Halma, JA Tuszynski, PE Marik - Nutrients, 2023 - mdpi.com
Cancer is amenable to low-cost treatments, given that it has a significant metabolic
component, which can be affected through diet and lifestyle change at minimal cost. The …

Therapeutic potential of natural products in inflammation: Underlying molecular mechanisms, clinical outcomes, technological advances, and future perspectives

NA Gouda, SO Alshammari, MAS Abourehab… - …, 2023 - Springer
Chronic inflammation is a common underlying factor in many major diseases, including
heart disease, diabetes, cancer, and autoimmune disorders, and is responsible for up to …

Wnt/β-catenin signaling inhibitors

X Zhang, N Dong, X Hu - Current topics in medicinal chemistry, 2023 - ingentaconnect.com
The Wnt/β-catenin signaling pathway plays a crucial role in the development, tissue
homeostasis, angiogenesis, and carcinogenesis of cancer. Mutations and excessive …