WHO working definition of vitality capacity for healthy longevity monitoring

I Bautmans, V Knoop, JA Thiyagarajan… - The lancet Healthy …, 2022 - thelancet.com
Intrinsic capacity, a crucial concept in healthy ageing, is defined by WHO as" the composite
of all the physical and mental capacities that an individual can draw on at any point in time" …

Defining and assessing intrinsic capacity in older people: a systematic review and a proposed scoring system

S Lopez-Ortiz, S Lista, S Penin-Grandes… - Ageing Research …, 2022 - Elsevier
Abstract Introduction The World Health Organization has introduced the term 'intrinsic
capacity'(IC) as a marker of healthy ageing. However, controversy exists on the definition …

[HTML][HTML] A rapid review of the measurement of intrinsic capacity in older adults

PP George, P Lun, SP Ong, WS Lim - The Journal of nutrition, health and …, 2021 - Elsevier
Objectives This study aims to address the knowledge gap and summarise the measurement
for intrinsic capacity for the five WHO domains across different populations. It specifically …

[HTML][HTML] Intrinsic capacity in older adults: recent advances

Y Zhou, L Ma - Aging and disease, 2022 - ncbi.nlm.nih.gov
The global increase in the aging population is expected to result in a shift from disease-
centered to function-centered approaches in response to intensive aging. Thus, the World …

Promising biomarkers of human aging: In search of a multi-omics panel to understand the aging process from a multidimensional perspective

NA Rivero-Segura, OY Bello-Chavolla… - Ageing research …, 2020 - Elsevier
The aging process has been linked to the occurrence of chronic diseases and functional
impairments, including cancer, sarcopenia, frailty, metabolic, cardiovascular, and …

Intrinsic capacity vs. multimorbidity: a function-centered construct predicts disability better than a disease-based approach in a community-dwelling older population …

J Zhao, JK Chhetri, Y Chang, Z Zheng, L Ma… - Frontiers in …, 2021 - frontiersin.org
Objective: This study aimed to assess the status of intrinsic capacity (IC)—a novel function-
centered construct proposed by the WHO and examine whether impairment in IC predicts …

Association of intrinsic capacity with incidence and mortality of cardiovascular disease: Prospective study in UK Biobank

R Ramírez‐Vélez, M Iriarte‐Fernández… - Journal of Cachexia …, 2023 - Wiley Online Library
Abstract Background The World Health Organization proposed the concept of intrinsic
capacity (IC; the composite of all the physical and mental capacities of the individual) as …

Screening for intrinsic capacity impairments as markers of increased risk of frailty and disability in the context of integrated care for older people: Secondary analysis of …

E González-Bautista, P de Souto Barreto, S Andrieu… - Maturitas, 2021 - Elsevier
Aim This longitudinal secondary analysis of the Multidomain Alzheimer Preventive Trial
(MAPT) aimed to test whether the Integrated Care for Older People (ICOPE) Step 1 …

Biological features of the outcome-based intrinsic capacity composite scores from a population-based cohort study: pas de deux of biological and functional aging

LC Meng, ST Huang, LN Peng, LK Chen… - Frontiers in …, 2022 - frontiersin.org
Introduction This study aims to develop and validate an integrative intrinsic capacity (IC)
scoring system, to investigate its associations with a wide spectrum of biomarkers and to …

[HTML][HTML] Exploring the conceptual framework and measurement model of intrinsic capacity defined by the World Health Organization: a scoping review

K Koivunen, LA Schaap, EO Hoogendijk… - Ageing Research …, 2022 - Elsevier
WHO has defined intrinsic capacity (IC) as the composite of all physical and mental
capacities of an individual covering five subdomains: cognition, locomotion, sensory, vitality …