Angiogenesis is a multistep process that requires intricate changes in cell shape to generate
new blood vessels. IF are a large family of proteins that play an important structural and …

The behavior of vascular EC is greatly altered in sites of pathological angiogenesis, such as
a developing tumor or atherosclerotic plaque. Until recently it was thought that this was …

Angiogenesis is initiated in response to a variety of external cues, including mechanical and
biochemical stimuli; however, the underlying signaling mechanisms remain unclear. Here …

Key points The endothelium plays a pivotal role in the vascular response to chemical and
mechanical stimuli. The endothelium is exquisitely sensitive to ACh, although the …

Objective Tortuous microvessels are characteristic of microvascular remodeling associated
with numerous physiological and pathological scenarios. Three‐dimensional (3D) …

Significance: Mechanical forces are important regulators of cell and tissue function.
Endothelial cells proliferate in response to tissue stretch and the mechanical properties of …

Developing therapies aimed at manipulating microvascular remodeling requires a better
understanding of angiogenesis and how angiogenesis relates to other network remodeling …

Objective Lymphatic and blood microvascular systems are critical for tissue function. Insights
into the coordination of both systems can be gained by investigating the relationships …

Tissue engineering research is increasingly relying on the use of advanced cultivation
technologies that provide rigorously-controlled cell microenvironments. Herein, we describe …

Microvascular network growth and remodeling are common denominators for most age-
related pathologies. For multiple pathologies (myocardial infarction, stroke, hypertension) …