The microbiome can promote or disrupt human health by influencing both adaptive and
innate immune functions. We tested whether bacteria that normally reside on human skin …

Humans are virtually identical in their genetic makeup, yet the small differences in our DNA
give rise to tremendous phenotypic diversity across the human population. By contrast, the …

Antibiotic pollution is becoming an increasingly severe threat globally. Antibiotics have
emerged as a new class of environmental pollutants due to their expanding usage and …

With an increasing prevalence during the past decades, atopic dermatitis has become a
global health issue. A literature search following a targeted approach was undertaken to …

An estimated 20–25% of the population is affected by chronic, non-communicable
inflammatory skin diseases. Chronic skin inflammation has many causes. Among the most …

Objective To provide an overview of filaggrin biology and the role of filaggrin variants in
atopic dermatitis (AD) and allergic disease. Data Sources We performed a PubMed literature …

Objective To discuss the efficacy and safety of novel and emerging topical and systemic
therapeutic agents for atopic dermatitis (AD). Data Sources The review of the published …

As an interface with the environment, the skin is a complex ecosystem colonized by many
microorganisms that coexist in an established balance. The cutaneous microbiome inhibits …

Skin is the largest organ in the human body, and the interplay between the environment
factors and human skin leads to some skin diseases, such as acne, psoriasis, and atopic …

The availability of allergen molecules ('components') from several protein families has
advanced our understanding of immunoglobulin E (IgE)‐mediated responses and enabled …