Abstract Phospholipid scramblase 1 (PLSCR1) is the most studied protein of the scramblase
family. Originally, it was identified as a membrane protein involved in maintaining plasma …

All major types of interferon (IFN) efficiently inhibit hepatitis C virus (HCV) replication in vitro
and in vivo. Remarkably, HCV replication is not sensitive to IFN-γ in the hepatoma cell line …

Hepatitis C virus (HCV) is widely used to investigate host–virus interactions. Cellular
responses to HCV infection have been extensively studied in vitro. However, in human liver …

Dengue virus (DV) is a positive-strand RNA virus of the Flavivirus genus. It is one of the most
prevalent mosquito-borne viruses, infecting globally 390 million individuals per year. The …

Hepatitis C virus (HCV) chronically infects 130–170 million people worldwide and is a major
public health burden. HCV is an RNA virus that infects hepatocytes within liver, and this …

Infectious diseases continue to claim many lives. Prevention of morbidity and mortality from
these diseases would benefit not just from new medicines and vaccines but also from a …

Highlights•Cells are equipped with pattern recognition receptors to sense invading
viruses.•Nucleic acids of RNA viruses are sensed by RIG-I like receptors in the …

Interferons (IFNs) restrict various kinds of viral infection via induction of hundreds of IFN-
stimulated genes (ISGs), while the functions of the majority of ISGs are broadly unclear …

The present report describes current concepts about the mechanism of liver cell injury
caused by host immune response against hepatitis C virus (HCV) infection in human beings …

Objective Interleukin-26 (IL-26) is a member of the IL-10 cytokine family, first discovered
based on its peculiar expression by virus-transformed T cells. IL-26 is overexpressed in …