[HTML][HTML] IFIT1 expression patterns induced by H9N2 virus and inactivated viral particle in human umbilical vein endothelial cells and bronchus epithelial cells

B Feng, Q Zhang, J Wang, H Dong, X Mu, G Hu… - Molecules and cells, 2018 - Elsevier
IFIT1 (also known as ISG56) is a member of the interferon-inducible protein with
tetratricopeptide repeats (IFITs) family. IFITs are strongly induced by type I interferon (IFN) …

[HTML][HTML] Dendritic cell-mediated, DNA-based vaccination against hepatitis C induces the multi-epitope-specific response of humanized, HLA transgenic mice

S Mishra, BJ Lavelle, J Desrosiers, MT Ardito, F Terry… - PLoS …, 2014 - journals.plos.org
Hepatitis C virus (HCV) is the etiologic agent of chronic liver disease, hepatitis C.
Spontaneous resolution of viral infection is associated with vigorous HLA class I-and class II …

IFN‐free therapy is associated with restoration of type I IFN response in HIV‐1 patients with acute HCV infection who achieve SVR

C Carlton‐Smith, JA Holmes, S Naggie… - Journal of viral …, 2018 - Wiley Online Library
Summary Interferon (IFN)‐free direct‐acting antiviral agents (DAA s) have revolutionized
chronic hepatitis C virus (HCV) treatment; early studies suggest excellent efficacy in acute …

[HTML][HTML] Suppression of Innate Immunity by the Hepatitis C Virus (HCV): Revisiting the Specificity of Host–Virus Interactive Pathways

S Barik - International Journal of Molecular Sciences, 2023 - mdpi.com
The hepatitis C virus (HCV) is a major causative agent of hepatitis that may also lead to liver
cancer and lymphomas. Chronic hepatitis C affects an estimated 2.4 million people in the …

Interaction of the phospholipid scramblase 1 with HIV-1 Tat results in the repression of Tat-dependent transcription

S Kusano, Y Eizuru - Biochemical and Biophysical Research …, 2013 - Elsevier
Human phospholipid scramblase 1 (PLSCR1) is an interferon (IFN)-stimulated gene and
possesses an IFN-mediated antiviral function. We show here that PLSCR1 directly interacts …

Initial hepatitis C virus infection of adult hepatocytes triggers a temporally structured transcriptional program containing diverse pro-and antiviral elements

B Tegtmeyer, G Vieyres, D Todt, C Lauber… - Journal of …, 2021 - Am Soc Microbiol
Transcriptional profiling provides global snapshots of virus-mediated cellular
reprogramming, which can simultaneously encompass pro-and antiviral components. To …

IFIT3 inhibits Epstein‐Barr virus reactivation via upregulating innate immunity

W Zhang, M Jiang, X Liao, Y Li, S Xin… - Journal of Medical …, 2023 - Wiley Online Library
Abstract Epstein‐Barr virus (EBV), a member of the γ‐herpesvirus family, can establish latent
infection in B lymphocytes and certain epithelial cells after primary infection. Under certain …

Peptide-pulsed dendritic cells induce the hepatitis C viral epitope-specific responses of naïve human T cells

S Mishra, PT Losikoff, AA Self, F Terry, MT Ardito… - Vaccine, 2014 - Elsevier
Hepatitis C virus (HCV) is a major cause of liver disease. Spontaneous resolution of
infection is associated with broad, MHC class I-(CD8+) and class II-restricted (CD4+) T cell …

IFN-α treatment inhibits acute Friend retrovirus replication primarily through the antiviral effector molecule Apobec3

MS Harper, BS Barrett, DS Smith, SX Li… - The Journal of …, 2013 - journals.aai.org
Therapeutic administration of IFN-α in clinical trials significantly reduced HIV-1 plasma viral
load and human T-lymphotropic virus type I proviral load in infected patients. The …

[HTML][HTML] Host restriction factors for hepatitis C virus

LY Zhou, LL Zhang - World Journal of Gastroenterology, 2016 - ncbi.nlm.nih.gov
Host-hepatitis C virus (HCV) interactions have both informed fundamental concepts of viral
replication and pathogenesis and provided novel insights into host cell biology. These …