Structure, function, and genetics of lipoprotein (a)
K Schmidt, A Noureen, F Kronenberg… - Journal of lipid …, 2016 - ASBMB
Lipoprotein (a)[Lp (a)] has attracted the interest of researchers and physicians due to its
intriguing properties, including an intragenic multiallelic copy number variation in the LPA …
intriguing properties, including an intragenic multiallelic copy number variation in the LPA …
Lipoprotein (a): resurrected by genetics
F Kronenberg, G Utermann - Journal of internal medicine, 2013 - Wiley Online Library
Plasma lipoprotein (a)[L p (a)] is a quantitative genetic trait with a very broad and skewed
distribution, which is largely controlled by genetic variants at the LPA locus on chromosome …
distribution, which is largely controlled by genetic variants at the LPA locus on chromosome …
Muvalaplin, an oral small molecule inhibitor of lipoprotein (a) formation: a randomized clinical trial
SJ Nicholls, SE Nissen, C Fleming, S Urva, J Suico… - JAMA, 2023 - jamanetwork.com
Importance Lipoprotein (a)(Lp [a]) is associated with atherosclerotic disease and aortic
stenosis. Lp (a) forms by bonding between apolipoprotein (a)(apo [a]) and apo B 100 …
stenosis. Lp (a) forms by bonding between apolipoprotein (a)(apo [a]) and apo B 100 …
[HTML][HTML] Lipoprotein (a) beyond the kringle IV repeat polymorphism: the complexity of genetic variation in the LPA gene
S Coassin, F Kronenberg - Atherosclerosis, 2022 - Elsevier
Abstract High lipoprotein (a)[Lp (a)] concentrations are one of the most important genetically
determined risk factors for cardiovascular disease. Lp (a) concentrations are an enigmatic …
determined risk factors for cardiovascular disease. Lp (a) concentrations are an enigmatic …
A genome-wide association study identifies protein quantitative trait loci (pQTLs)
There is considerable evidence that human genetic variation influences gene expression.
Genome-wide studies have revealed that mRNA levels are associated with genetic variation …
Genome-wide studies have revealed that mRNA levels are associated with genetic variation …
A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms [S]
High lipoprotein (a)[Lp (a)] concentrations are an independent risk factor for cardiovascular
outcomes. Concentrations are strongly influenced by apo (a) kringle IV repeat isoforms. We …
outcomes. Concentrations are strongly influenced by apo (a) kringle IV repeat isoforms. We …
Polymorphism in the apolipoprotein (a) gene, plasma lipoprotein (a), cardiovascular disease, and low-dose aspirin therapy
DI Chasman, D Shiffman, RYL Zee, JZ Louie, MM Luke… - Atherosclerosis, 2009 - Elsevier
OBJECTIVE: A minor allele variant (rs3798220) of apolipoprotein (a) has been reported to
be associated with elevated plasma lipoprotein (a)[Lp (a)] and increased cardiovascular risk …
be associated with elevated plasma lipoprotein (a)[Lp (a)] and increased cardiovascular risk …
Lipid metabolism in cognitive decline and dementia
F Panza, A D'Introno, AM Colacicco, C Capurso… - Brain research …, 2006 - Elsevier
This review will focus on the current knowledge on circulating serum and plasma risk factors
of cognitive decline of degenerative (Alzheimer's disease, AD) or vascular origin (vascular …
of cognitive decline of degenerative (Alzheimer's disease, AD) or vascular origin (vascular …
Diet and Lp (a): does dietary change modify residual cardiovascular risk conferred by Lp (a)?
B Enkhmaa, KS Petersen, PM Kris-Etherton… - Nutrients, 2020 - mdpi.com
Lipoprotein (a)[Lp (a)] is an independent, causal, genetically determined risk factor for
cardiovascular disease (CVD). We provide an overview of current knowledge on Lp (a) and …
cardiovascular disease (CVD). We provide an overview of current knowledge on Lp (a) and …
A polymorphism in the protease-like domain of apolipoprotein (a) is associated with severe coronary artery disease
MM Luke, JP Kane, DM Liu, CM Rowland… - … , and vascular biology, 2007 - Am Heart Assoc
Objectives—The purpose of this study was to identify genetic variants associated with
severe coronary artery disease (CAD). Methods and Results—We used 3 case-control …
severe coronary artery disease (CAD). Methods and Results—We used 3 case-control …