The renaissance of lipoprotein (a): brave new world for preventive cardiology?

KL Ellis, MB Boffa, A Sahebkar, ML Koschinsky… - Progress in Lipid …, 2017 - Elsevier
Abstract Lipoprotein (a)[Lp (a)] is a highly heritable cardiovascular risk factor. Although
discovered more than 50 years ago, Lp (a) has recently re-emerged as a major focus in the …

Circulating biomarkers of cognitive decline and dementia

V Solfrizzi, A D'Introno, AM Colacicco, C Capurso… - Clinica Chimica …, 2006 - Elsevier
Plasma and serum biochemical markers proposed for cognitive decline of degenerative
(Alzheimer's disease, AD) or vascular origin and predementia syndromes (mild cognitive …

When should we measure lipoprotein (a)?

KM Kostner, W März, GM Kostner - European heart journal, 2013 - academic.oup.com
Recently published epidemiological and genetic studies strongly suggest a causal
relationship of elevated concentrations of lipoprotein (a)[Lp (a)] with cardiovascular disease …

[HTML][HTML] Genome-wide association study of plasma lipoprotein (a) levels identifies multiple genes on chromosome 6q [S]

C Ober, AS Nord, EE Thompson, L Pan, Z Tan… - Journal of lipid …, 2009 - ASBMB
Plasma lipoprotein (a)(Lp [a]) level is an independent risk factor of cardiovascular disease
that is under strong genetic control. We conducted a genome-wide association study of …

[HTML][HTML] Lipoprotein (a): Pathophysiology, measurement, indication and treatment in cardiovascular disease. A consensus statement from the Nouvelle Société …

V Durlach, D Bonnefont-Rousselot, F Boccara… - Archives of …, 2021 - Elsevier
Lipoprotein (a) is an apolipoprotein B100-containing low-density lipoprotein-like particle that
is rich in cholesterol, and is associated with a second major protein, apolipoprotein (a) …

Genetic aspects of ischemic stroke: coagulation, homocysteine, and lipoprotein metabolism as potential risk factors

S Stankovic, N Majkic-Singh - Critical Reviews in Clinical …, 2010 - Taylor & Francis
Stroke is one of the most common causes of death and long term disability throughout the
world. It may be the outcome of a number of monogenic disorders or, more commonly, a …

Pentanucleotide TTTTA repeat polymorphism of apolipoprotein (a) gene and plasma lipoprotein (a) are associated with ischemic and hemorrhagic stroke in Chinese …

L Sun, Z Li, H Zhang, A Ma, Y Liao, D Wang, B Zhao… - Stroke, 2003 - Am Heart Assoc
Background and Purpose—It is still inconclusive whether high plasma lipoprotein (a)[Lp (a)]
level is a risk factor for stroke. Small sample size and different ethnic groups and …

Genetic variants in the apolipoprotein (a) gene and coronary heart disease

Y Li, MM Luke, D Shiffman, JJ Devlin - Circulation: Cardiovascular …, 2011 - Am Heart Assoc
Two independent single-nucleotide polymorphisms (SNPs) in the gene encoding
apolipoprotein (a)(LPA) have been shown to be associated with coronary heart disease …

Evidence for several independent genetic variants affecting lipoprotein (a) cholesterol levels

W Lu, YC Cheng, K Chen, H Wang… - Human molecular …, 2015 - academic.oup.com
Abstract Lipoprotein (a)[Lp (a)] is an independent risk factor for atherosclerosis-related
events that is under strong genetic control (heritability= 0.68–0.98). However, causal …

Genetic factors explain a major fraction of the 50% lower lipoprotein (a) concentrations in Finns

G Erhart, C Lamina, T Lehtimäki… - … , and vascular biology, 2018 - Am Heart Assoc
Objective—Lp (a)(lipoprotein (a)) concentrations are widely genetically determined by the
LPA isoforms and show 5-fold interpopulation differences. Two-to 3-fold differences have …