[HTML][HTML] The effect of LPA Thr3888Pro on lipoprotein (a) and coronary artery disease is modified by the LPA KIV-2 variant 4925G> A

R Grüneis, C Lamina, S Di Maio, S Schönherr… - Atherosclerosis, 2022 - Elsevier
Background and aims High lipoprotein (a)[Lp (a)] concentrations are associated with
increased coronary artery disease (CAD) risk. Lp (a) is regulated mainly genetically by the …

LPA and PLG Sequence Variation and Kringle IV-2 Copy Number in Two Populations

DC Crawford, Z Peng, JF Cheng, D Boffelli, M Ahearn… - Human …, 2008 - karger.com
Abstract Background/Aims: Lp (a) levels have long been recognized as a potential risk factor
for coronary heart disease that is almost completely under genetic control. Much of the …

[HTML][HTML] Therapeutic Potential of Lipoprotein (a) Inhibitors

SJ Nicholls - Drugs, 2024 - Springer
Increasing evidence has implicated lipoprotein (a)[Lp (a)] in the causality of atherosclerosis
and calcific aortic stenosis. This has stimulated immense interest in developing novel …

[HTML][HTML] Identification of copy number variants defining genomic differences among major human groups

L Armengol, S Villatoro, JR González, L Pantano… - PloS one, 2009 - journals.plos.org
Background Understanding the genetic contribution to phenotype variation of human groups
is necessary to elucidate differences in disease predisposition and response to …

Lipoprotein (a)

M Koschinsky, SM Marcovina - Clinical lipidology: a companion …, 2009 - books.google.com
Although numerous studies since the 1960s have identified increased plasma
concentrations of lipoprotein (a)[Lp (a)] as a risk factor for coronary heart disease (CHD), the …

[HTML][HTML] Genome-wide linkage analysis for identifying quantitative trait loci involved in the regulation of lipoprotein a (Lpa) levels

S López, A Buil, J Ordoñez, JC Souto… - European journal of …, 2008 - nature.com
Lipoprotein Lp (a) levels are highly heritable and are associated with cardiovascular risk.
We performed a genome-wide linkage analysis to delineate the genomic regions that …

Comparison of different Lp (a) elimination techniques: A retrospective evaluation

H Borberg - Transfusion and Apheresis Science, 2009 - Elsevier
Lipoprotein (a), abbreviated Lp (a), is accepted as a potential selective or additional risk
factor for premature atherosclerosis. Though it may be considered to be closely related to …

Sequence and functional changes in a putative enhancer region upstream of the apolipoprotein (a) gene

LH Puckey, BL Knight - Atherosclerosis, 2003 - Elsevier
Two enhancer regions upstream of the apolipoprotein (a)(apo (a)) gene were amplified and
sequenced from subjects who were known to express abnormally high or low amounts of …

Quo vadis haemapheresis: Current developments in haemapheresis

H Borberg - Transfusion and Apheresis Science, 2006 - Elsevier
The techniques of haemapheresis originated in the development of centrifugal devices
separating cells from plasma and later on plasma from cells. Subsequently membrane …

[HTML][HTML] Apo [a] size and PNR explain African American-Caucasian differences in allele-specific apo [a] levels for small but not large apo [a]

J Rubin, HJ Kim, TA Pearson, S Holleran… - Journal of lipid …, 2006 - ASBMB
Apolipoprotein [a](apo [a]) gene size is a major predictor of lipoprotein [a] level. To
determine genetic predictors of allele-specific apo [a] levels beyond gene size, we evaluated …