Non-alcoholic fatty liver disease (NAFLD) is not only a consequence of insulin resistance,
but it is also an important cause of insulin resistance and major non-communicable diseases …

Adhesion G protein-coupled receptors: structure, signaling, physiology, and
pathophysiology Page 1 REVIEW ARTICLE ADHESION G PROTEIN-COUPLED …

Adhesion G protein-coupled receptors (aGPCRs) are essential for a variety of physiological
processes such as immune responses, organ development, cellular communication …

Adhesion G protein‐coupled receptors (aGPCRs) are a class of structurally and functionally
highly intriguing cell surface receptors with essential functions in health and disease. Thus …

The discovery and rejuvenation of metabolically active brown adipose tissue (BAT) in adult
humans have offered a new approach to treating obesity and metabolic diseases. Beyond …

G protein-coupled receptors (GPCRs) represent one of the most targeted drug classes in the
human genome, accounting for greater than 40% of all Food and Drug Administration …

Intermittent fasting (IF), as a dietary intervention for weight loss, takes effects primarily
through increasing energy expenditure. However, whether inter‐organ systems play a key …

G protein-coupled receptors (GPCRs) are expressed essentially on all cells, facilitating
cellular responses to external stimuli, and are involved in nearly every biological process …

The mechanistic details of the tethered agonist mode of activation for the adhesion GPCR
ADGRF5/GPR116 have not been completely deciphered. We set out to investigate the …

In Brief Hormones secreted by muscle cells (myokines) are involved in the adaptive
response to nutritional and metabolic changes. In this review, we discuss how one family of …